ArticleIDCases2017
A positive rapid strep test in a young adult with acute pharyngitis: Be careful what you wish for!
Article in IDCases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- Prevalence of Asymptomatic Group AJournal of clinical medicine · 2025Article
- Review
- Pharyngitis: Approach to diagnosis and treatment.Canadian family physician Medecin de famille canadien · 2020Review
- Case Report: Periorbital Edema as an Overlooked Presentation of Epstein-Barr Virus.Case reports in ophthalmologyArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In young adults with acute pharyngitis, the main differential diagnosis is between GAS pharyngitis, EBV infectious mononucleosis, or other causes of viral pharyngitis. A positive RST does not differentiate GAS colonization from infection as is well illustrated by this case. Laboratory test results must be interpreted in the appropriate clinical context to be diagnostically meaningful. The RST only detects group A streptococci, but does not, of itself, implicate a causative role in the patient's pharyngitis. Without clinical correlation based on the clinical findings of GAS pharyngitis a positive RST may mislead the unwary physician to unnecessarily treat colonization rather than infection. I report an interesting case of a young adult who presented to the ED with no fever and acute pharyngitis. His RST was positive, and he was treated with procaine penicillin and released. Three days later he was re-admitted to the hospital with severe Herpes gingivostomatitis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.