ArticleJournal of thoracic disease2017
Standardized uptake value and radiological density attenuation as predictive and prognostic factors in patients with solitary pulmonary nodules: our experience on 1,592 patients.
Article in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 28 citations in OpenAlex.
- Comparative Analysis of F-18 FDG PET-Based Metabolic Parameters in the Differential Diagnosis of Esophageal Squamous Cell Carcinoma and Adenocarcinoma.World journal of nuclear medicine · 2026Article
- Multiomics Analysis Reveals Molecular Changes during Early Progression of Precancerous Lesions to Lung Adenocarcinoma in Never-Smokers.Cancer research · 2025Article
- The presence of circulating genetically abnormal cells in blood predicts risk of lung cancer in individuals with indeterminate pulmonary nodules.BMC pulmonary medicine · 2023Article
- Classification of solid pulmonary nodules using a machine-learning nomogram based onAnnals of translational medicine · 2022Article
- Is It Possible to Establish a Reliable Correlation between Maximum Standardized Uptake Value of 18-Fluorine Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and Histological Types of Non-Small Cell Lung Cancer? Analysis of the Italian VATS Group Database.Diagnostics (Basel, Switzerland) · 2021Article
- Observational
- Solitary Pulmonary Nodule: Morphological Effects on Metabolic Activity AssessmentMolecular imaging and radionuclide therapy · 2019Article
- Circulating tumor cell levels and carcinoembryonic antigen: An improved diagnostic method for lung adenocarcinoma.Thoracic cancer · 2018Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMultislice computed tomography (MSCT) increased detection of solitary pulmonary nodules (SPNs), changing the management based on radiological and clinical factors. When 18-fluorine fluorodeoxyglucose positron emission tomography combined with computed tomography (
methodsA retrospective study on 1,592 SPN patients was carried out following approval by the Italian Registry of VATS Lobectomies.
resultsAll patients underwent VATS lobectomy. On histologic examination, 98.1% had primary or second metachronous primary lung cancers. In addition, 10.7% presented occult lymph node metastases (pN1 or pN2) on histological examination. Nodule attenuation on CT was associated with the histology of the lesion (p= 0.030); in particular, pure ground glass opacities (pGGOs) and partially solid nodules were related to adenocarcinomatous histotypes. Conversely, a significant relationship between SUVmax and age, nodule size, pathological node status (pN) was found (P=0.007, P=0.000 and P=0.002 respectively).
conclusionsNodule attenuation can predict the histology of the lesion whereas SUVmax may relate to the propensity to lymph node metastases.
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