Evidence map›Paper›PMID 28932505›Full record

ArticleInterventional medicine & applied science2017

The features of morphological changes in the urinary bladder under combined effect of heavy metal salts.

Anatolii Romaniuk, Vladyslav Sikora, Mykola Lyndin, Vladyslav Smiyanov, Volodymyr Sikora, Yulia Lyndina, Artem Piddubnyi, Nataliya Gyryavenko, Anna Korobchanska

Abstract read
In one paragraph

Article in Interventional medicine & applied science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Lead acetate versus cadmium sulfate in the modulation of main physiological pathways controlling detrusor muscle contractility in rat.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Anatolii RomaniukDepartment of Pathology, Sumy State University, Sumy, Ukraine.
Vladyslav SikoraDepartment of Pathology, Sumy State University, Sumy, Ukraine.
Mykola LyndinDepartment of Pathology, Sumy State University, Sumy, Ukraine.
Vladyslav SmiyanovMedical Institute, Sumy State University, Sumy, Ukraine.
Volodymyr SikoraSurgery Department with Pediatric Surgery and Urology, Sumy State University, Sumy, Ukraine.
Yulia LyndinaDepartment of Normal Anatomy, Sumy State University, Sumy, Ukraine.
Artem PiddubnyiDepartment of Pathology, Sumy State University, Sumy, Ukraine.
Nataliya GyryavenkoDepartment of Pathology, Sumy State University, Sumy, Ukraine.
Anna KorobchanskaDepartment of Normal Anatomy, Kharkiv National Medical University, Kharkiv, Ukraine.
Sumy State University · UAKharkiv National Medical University · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study is aimed to the investigation of the features of morphological changes in the urinary bladder of mature rats.

resultsReceived results shown that the experimental group of rats that had the intake of heavy metal salts (HMS) mixture during 30 and 90 days were observed histological and immunohistochemical changes in all structures of the urinary bladder. Depending on the period of influence of heavy metal ions on the wall of the organ, the pathological changes developed in cellular layers of the wall can lead to degenerative and later to atrophic and sclerotic changes.

conclusionsThis study demonstrates that high concentrations of HMS can significantly influence the body. The histological and immunohistochemical studies showed that the influence of the HMS combination leads to deep morphological changes in all structures of the urinary bladder. These changes depend on the period of intake of HMS. Analysis of the obtained results demonstrates the dependence of expression of morphological changes in the urinary bladder on the experiment duration. The final result of these changes may lead to the disorders of bladder's functions.

Indexed as

environmentheavy metal saltshistological studiesHps90αimmunohistochemical studiesKi-67urinary bladder

Identifiers

PMID28932505
PMCPMC5598125
OpenAlexW3190879020

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.