Evidence map›Paper›PMID 28932489›Full record

ArticleInterventional medicine & applied science2017

The impact of cardiac resynchronization therapy on routine laboratory parameters.

András Mihály Boros, Péter Perge, Klaudia Vivien Nagy, Astrid Apor, Zsolt Bagyura, Endre Zima, Levente Molnár, Tamás Tahin, Dávid Becker, László Gellér and 2 more

Abstract read
In one paragraph

Article in Interventional medicine & applied science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

András Mihály BorosHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Péter PergeHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Klaudia Vivien NagyHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Astrid AporHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Zsolt BagyuraHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Endre ZimaHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Levente MolnárHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Tamás TahinHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Dávid BeckerHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
László GellérHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Béla MerkelyHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Gábor SzéplakiHeart and Vascular Center, Semmelweis University, Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac resynchronization therapy (CRT) in chronic heart failure has been shown to improve mortality and morbidity. However, comprehensive data are not available as concerns how circulating biomarkers reflecting different organ functions, such as serum uric acid, blood urea nitrogen (BUN), albumin, cholesterol, or various liver enzymes, change over time as a consequence of CRT. The aim of this prospective study was to overview these possible changes.

methodsA total of 20 routine laboratory parameters were measured in 122 control subjects and in 129 patients with chronic heart failure before CRT, 6 months, and 2 years later.

resultsThe levels of serum uric acid [before: 432 (331-516) mmol/L, 6-month: 372 (304-452) mmol/L, 2-year: 340 (290-433) mmol/L;

conclusionsCRT influences the levels of routinely used biomarkers suggesting improvements in renal function, liver capacity, and metabolic changes. These changes could mirror the multiorgan improvement after CRT.

Indexed as

biomarkerchronic heart failureCRTorganic functionresynchronization

Identifiers

PMID28932489
PMCPMC5598115

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.