ArticleCaspian journal of internal medicine2017
Acupuncture and botulinum toxin A injection in the treatment of chronic migraine: A randomized controlled study.
Article in Caspian journal of internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 7 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Acupuncture Versus Standard Medical Care in the Prophylactic Treatment of Migraine: A Systematic Review and Meta-Analysis.European journal of neurology · 2025Pooled it
- Effectiveness and safety of pharmacological prophylaxis for chronic migraine: a systematic review and network meta-analysis.Journal of neurology · 2024Pooled it
- Pooled it
- Botox (OnabotulinumtoxinA) for Treatment of Migraine Symptoms: A Systematic Review.Pain research & management · 2022Pooled it
- Efficacy of acupuncture for migraine prophylaxis: a trial sequential meta-analysis.Journal of neurology · 2021Pooled it
- Acupuncture versus propranolol in migraine prophylaxis: an indirect treatment comparison meta-analysis.Journal of neurology · 2020Pooled it
- Acupuncture vs. Pharmacological Prophylaxis of Migraine: A Systematic Review of Randomized Controlled Trials.Frontiers in neurology · 2020Pooled it
- Non-Pharmacological Treatment for Chronic Migraine.Current pain and headache reports · 2023Review
- Acupuncture as an alternative or in addition to conventional treatment for chronic non-specific low back pain: A systematic review and meta-analysis.Integrative medicine research · 2023Review
- Article
- Is Acupuncture Safe and Effective Treatment for Migraine? A Systematic Review of Randomized Controlled Trials.Cureus · 2022Review
- Acupuncture and Its Role in the Treatment of Migraine Headaches.Neurology and therapy · 2020Review
- Acupuncture for Migraine: a Review of the Data and Clinical Insights.Current pain and headache reports · 2020Review
- Acupuncture versus Various Control Treatments in the Treatment of Migraine: A Review of Randomized Controlled Trials from the Past 10 Years.Journal of pain research · 2020Review
- Classic Chinese Acupuncture versus Different Types of Control Groups for the Treatment of Chronic Pain: Review of Randomized Controlled Trials (2000-2018).Evidence-based complementary and alternative medicine : eCAM · 2019Review
- What Is the Appropriate Acupuncture Treatment Schedule for Chronic Pain? Review and Analysis of Randomized Controlled Trials.Evidence-based complementary and alternative medicine : eCAM · 2019Review
- Guideline on the use of onabotulinumtoxinA in chronic migraine: a consensus statement from the European Headache Federation.The journal of headache and pain · 2018Article
- Acupuncture for chronic nonpulsatile tinnitus: A randomized clinical trial.Caspian journal of internal medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMigraine is a common type of headache. Sometimes adequate pain relief is not achieved by conventional treatments. Acupuncture and botulinum toxin-A injection are known as non-pharmacological interventions for this purpose. The aim of this research was to compare the effect of acupuncture with botulinum toxin-A injection and pharmacological treatment in controlling chronic migraine.
methodsThis clinical trial was conducted on patients with chronic migraine in the North of Iran during 2014-2015. Eligible patients were randomly allocated to groups receiving acupuncture (A) or botulinum toxin A (B) and controls (C) by designed quadripartite blocks. All patients were evaluated at baseline, one, two and three months after treatment using visual analogue scale (VAS) score and other parameters. The analysis of data was performed in SPSS software Version 19.
resultsOne hundred fifty patients (48 males and 102 females) completed this study. During the 3- month study, the pain severity significantly diminished in three groups (P=0.0001), with greater reduction in group A (P=0.0001). The number of days per month with migraine, absence from work and the need for medication significantly decreased in three groups at 3 times of evaluation (p<0.05) with fewer side effects in group A (P=0.021).
conclusionAcupuncture, botulinum toxin-A injection and pharmacological treatment have beneficial effects on chronic migraine; however, acupuncture showed more effectiveness and fewer complications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.