Evidence map›Paper›PMID 28932334›Full record

ArticleThe open ophthalmology journal2017

Corneal Biomechanics in Ectatic Diseases: Refractive Surgery Implications.

Renato Ambrósio, Fernando Faria Correia, Bernardo Lopes, Marcella Q Salomão, Allan Luz, Daniel G Dawson, Ahmed Elsheikh, Riccardo Vinciguerra, Paolo Vinciguerra, Cynthia J Roberts

Open access · diamondAbstract read
In one paragraph

Article in The open ophthalmology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 74 citations in OpenAlex.

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  10. Squishy matters - Corneal mechanobiology in health and disease.Progress in retinal and eye research · 2024
    Review
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  14. Reliability analysis of successive Corvis ST® measurements in keratoconus 2 years after accelerated corneal crosslinking compared to untreated keratoconus corneas.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  15. Assessment of the corneal biomechanical features of granular corneal dystrophy type 2 using dynamic ultra-high-speed Scheimpflug imaging.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 5 countries.

Renato AmbrósioInstituto de Olhos Renato Ambrósio, Rio de Janeiro, Brazil.
Fernando Faria CorreiaLife and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal.
Bernardo LopesInstituto de Olhos Renato Ambrósio, Rio de Janeiro, Brazil.
Marcella Q SalomãoInstituto de Olhos Renato Ambrósio, Rio de Janeiro, Brazil.
Allan LuzRio de Janeiro Corneal Tomography and Biomechanics Study Group, Rio de Janeiro, Brazil.
Daniel G DawsonThe University of Florida Department of Ophthalmology, Gainesville, FL, USA.
Ahmed ElsheikhSchool of Engineering, University of Liverpool - Liverpool, United Kingdom.
Riccardo VinciguerraDepartment of Surgical Sciences, Division of Ophthalmology, University of Insubria, Varese, Italy.
Paolo VinciguerraDepartment of Surgical Sciences, Division of Ophthalmology, University of Insubria, Varese, Italy.
Cynthia J RobertsDepartment of Ophthalmology & Visual Science, Department of Biomedical Engineering, The Ohio State University - Columbus, OH, USA.
Universidade Federal de São Paulo · BRHospital Braga · PTHumanitas University · ITInstituto de Olhos de Goiânia · BRThe Ohio State University · USUniversity of Florida · USUniversity of Insubria · ITUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEctasia development occurs due to a chronic corneal biomechanical decompensation or weakness, resulting in stromal thinning and corneal protrusion. This leads to corneal steepening, increase in astigmatism, and irregularity. In corneal refractive surgery, the detection of mild forms of ectasia pre-operatively is essential to avoid post-operative progressive ectasia, which also depends on the impact of the procedure on the cornea.

methodThe advent of 3D tomography is proven as a significant advancement to further characterize corneal shape beyond front surface topography, which is still relevant. While screening tests for ectasia had been limited to corneal shape (geometry) assessment, clinical biomechanical assessment has been possible since the introduction of the Ocular Response Analyzer (Reichert Ophthalmic Instruments, Buffalo, USA) in 2005 and the Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany) in 2010. Direct clinical biomechanical evaluation is recognized as paramount, especially in detection of mild ectatic cases and characterization of the susceptibility for ectasia progression for any cornea.

conclusionsThe purpose of this review is to describe the current state of clinical evaluation of corneal biomechanics, focusing on the most recent advances of commercially available instruments and also on future developments, such as Brillouin microscopy.

Identifiers

PMID28932334
PMCPMC5585467
OpenAlexW2733983973

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.