Evidence map›Paper›PMID 28932265›Full record

ArticleBiotechnology for biofuels2017

Removal of glucuronic acid from xylan is a strategy to improve the conversion of plant biomass to sugars for bioenergy.

Jan J Lyczakowski, Krzysztof B Wicher, Oliver M Terrett, Nuno Faria-Blanc, Xiaolan Yu, David Brown, Kristian B R M Krogh, Paul Dupree, Marta Busse-Wicher

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Jan J LyczakowskiDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW UK.
Krzysztof B WicherThe Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QN UK.
Oliver M TerrettDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW UK.
Nuno Faria-BlancDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW UK.
Xiaolan YuDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW UK.
David BrownDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW UK.
Kristian B R M KroghDepartment of Protein Biochemistry and Stability, Novozymes A/S, Krogshøjvej 36, 2880 Bagsværd, Denmark.
Paul DupreeDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW UK.ORCID 0000-0001-9270-6286
Marta Busse-WicherDepartment of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW UK.ORCID 0000-0001-6290-2462
University of Cambridge · GBNovozymes (Denmark) · DK

Funding

Biotechnology and Biological Sciences Research Council BB/L014130/1
6 · The paper itself

Abstract

backgroundPlant lignocellulosic biomass can be a source of fermentable sugars for the production of second generation biofuels and biochemicals. The recalcitrance of this plant material is one of the major obstacles in its conversion into sugars. Biomass is primarily composed of secondary cell walls, which is made of cellulose, hemicelluloses and lignin. Xylan, a hemicellulose, binds to the cellulose microfibril and is hypothesised to form an interface between lignin and cellulose. Both softwood and hardwood xylan carry glucuronic acid side branches. As xylan branching may be important for biomass recalcitrance and softwood is an abundant, non-food competing, source of biomass it is important to investigate how conifer xylan is synthesised.

resultsHere, we show using Arabidopsis

conclusionRemoval of glucuronic acid from xylan results in the largest increase in release of fermentable sugars from Arabidopsis plants that grow to the wild-type size. Additionally, plant material used in this work did not undergo any chemical pretreatment, and thus increased monosaccharide release from

Indexed as

BiofuelsConifersGlucuronic acidGUXSoftwoodXylan

Identifiers

PMID28932265
PMCPMC5606085
OpenAlexW2756136957

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.