Evidence map›Paper›PMID 28932226›Full record

ReviewFrontiers in immunology2017

Immunomodulatory Properties of

Mohammad H Saleh, Iran Rashedi, Armand Keating

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 94 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. High-Risk Human Papillomavirus Clearance with aDiseases (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Exploring the Anticancer Potential ofCurrent issues in molecular biology · 2025
    Review
  10. Review
  11. Article
  12. Enhanced Anti-Cancer Potential: Investigating the Combined Effects withInternational journal of molecular sciences · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer.International journal of molecular sciences · 2023
    Review
  19. Article
  20. COVID-19 and Cancer Diseases-The Potential ofInternational journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mohammad H SalehInstitute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
Iran RashediCell Therapy Program, Princess Margaret Cancer Centre, Krembil Research Institute, University Health Network, Toronto, ON, Canada.
Armand KeatingInstitute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
Krembil Research InstitutePrincess Margaret Cancer Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional uses of herbal medicine have depended mostly on anecdotal evidence for much of history. The increasing application of scientific rigor to the study some of these traditional therapies in recent years has revealed potent bioactivity, notably demonstrated by the 2015 Nobel Prize for the discovery of an antimalarial compound from traditional Chinese herbs. Given the recent successes of immunotherapy and checkpoint blockade, there is a renewed interest in identifying new drugs with immunomodulatory effects. As an estimated 45-60% of cancer patients worldwide are reported to use complementary alternative medicine alongside traditional therapy, this review will highlight the literature on the immunomodulatory effects of one of these compounds. We report on the induction of a largely pro-inflammatory cytokine profile by the polysaccharopeptide (PSP) isolated from the

Indexed as

Coriolus versicolorimmunomodulationmushroompolysaccharide peptidepolysaccharopeptideYun zhi

Identifiers

PMID28932226
PMCPMC5592279
OpenAlexW2751572188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.