ReviewPain research & management2017
Central Sensitization-Based Classification for Temporomandibular Disorders: A Pathogenetic Hypothesis.
Review in Pain research & management, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Association between temporomandibular disorders, sleep disturbance, and psychological distress in children and adolescents: a systematic review.BMC oral health · 2026Pooled it
- Effects of trigeminal neurostimulation on heart rate variability: comparing cutaneous (Tragus) and tongue (Antero-Dorsal mucosa) stimulation.BMC oral health · 2024Trial
- Effect of photobiomodulation therapy on painful temporomandibular disorders.Scientific reports · 2021Trial
- The Application of Radiofrequency Waves in Supportive Treatment of Temporomandibular Disorders.Pain research & management · 2020Trial
- Alterations in Surface Electromyography Are Associated with Subjective Masticatory Muscle Pain.Pain research & management · 2019Trial
- A Device Improves Signs and Symptoms of TMD.Pain research & management · 2019Trial
- Does Anterior Disc Displacement with Reduction Affect Postoperative Pain Perception After Root Canal Therapy? A Prospective Comparative Clinical Study.Diagnostics (Basel, Switzerland) · 2026Article
- Does adding ultrasonography to clinical-psychosocial measures improve discrimination for temporomandibular disorders?Imaging science in dentistry · 2026Article
- Association between bruxism and inflammatory rheumatic diseases: is there a possible bidirectional relationship?Rheumatology international · 2025Review
- Article
- Criterion Validity of the Isometric Contraction Test for Diagnosis of Axis I DC/TMD Considering Specific Muscles.Journal of oral rehabilitation · 2025Article
- Distinguishing acute and chronic TMD in adolescent patients.Scientific reports · 2025Article
- Role of Central Sensitization Syndrome in Patients With Autonomic Symptoms.Neurology. Clinical practice · 2025Article
- Prevalence of central sensitization and somatization in adults with temporomandibular disorders-a prospective observational study.Journal of oral & facial pain and headache · 2024Observational
- Relationships between personality factors and DC/TMD Axis II scores of psychosocial impairment among patients with pain related temporomandibular disorders.Scientific reports · 2024Article
- Impact of applying different levels of threshold-based artifact correction on the processing of heart rate variability data in individuals with temporomandibular disorder.Scientific reports · 2024Observational
- The effect of human assumed central sensitization on transforaminal epidural steroid injection in chronic lumbar radiculopathy: An observational study.Journal of back and musculoskeletal rehabilitation · 2024Observational
- Myopia & painful muscle form of temporomandibular disorders: connections between vision, masticatory and cervical muscles activity and sensitivity and sleep quality.Scientific reports · 2023Article
- Comparison of Pre- and Posttreatment Airway Volume in Patients with Temporomandibular Joint Disorders Treated with Ultra-Low Frequency Transcutaneous Electrical Nerve Stimulation Using Cone Beam Computed Tomography.International archives of otorhinolaryngology · 2023Article
- The Biology of Stress Intolerance in Patients with Chronic Pain-State of the Art and Future Directions.Journal of clinical medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dysregulation of Autonomic Nervous System (ANS) and central pain pathways in temporomandibular disorders (TMD) is a growing evidence. Authors include some forms of TMD among central sensitization syndromes (CSS), a group of pathologies characterized by central morphofunctional alterations. Central Sensitization Inventory (CSI) is useful for clinical diagnosis. Clinical examination and CSI cannot identify the central site(s) affected in these diseases. Ultralow frequency transcutaneous electrical nerve stimulation (ULFTENS) is extensively used in TMD and in dental clinical practice, because of its effects on descending pain modulation pathways. The Diagnostic Criteria for TMD (DC/TMD) are the most accurate tool for diagnosis and classification of TMD. However, it includes CSI to investigate central aspects of TMD. Preliminary data on sensory ULFTENS show it is a reliable tool for the study of central and autonomic pathways in TMD. An alternative classification based on the presence of Central Sensitization and on individual response to sensory ULFTENS is proposed. TMD may be classified into 4 groups: (a) TMD with Central Sensitization ULFTENS Responders; (b) TMD with Central Sensitization ULFTENS Nonresponders; (c) TMD without Central Sensitization ULFTENS Responders; (d) TMD without Central Sensitization ULFTENS Nonresponders. This pathogenic classification of TMD may help to differentiate therapy and aetiology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.