Evidence map›Paper›PMID 28932112›Full record

ReviewInternational journal of chronic obstructive pulmonary disease2017

Acute exacerbations of COPD: risk factors for failure and relapse.

Marco Mantero, Paola Rogliani, Marta Di Pasquale, Eva Polverino, Ernesto Crisafulli, Monica Guerrero, Andrea Gramegna, Mario Cazzola, Francesco Blasi

Abstract readReview
In one paragraph

Review in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Implementing acute exacerbations of COPD care bundles: evidence, effectiveness and future directions.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  4. Severe COPD Exacerbators Requiring Multiple ICU Admissions Over Time: Insights of a French Cohort.International journal of chronic obstructive pulmonary disease · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Real-World Evaluation of an EHR-Enabled Chronic Obstructive Pulmonary Disease Assessment Test.International journal of chronic obstructive pulmonary disease · 2025
    Observational
  12. Article
  13. Article
  14. Article
  15. Article
  16. Factors Associated with the Non-Exacerbator Phenotype of Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marco ManteroDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano.
Paola RoglianiRespiratory Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Marta Di PasqualeDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano.
Eva PolverinoRespiratory Disease Department, Servei de Pneumologia, Hospital Universitari Vall d'Hebron (HUVH), Institut de Recerca Vall d'Hebron (VHIR), Barcelona, Spain.
Ernesto CrisafulliDepartment of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma, Parma, Italy.
Monica GuerreroHospital d'Igualada, Consorci Socisanitari de l'Anoia, Barcelona, Spain.
Andrea GramegnaDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano.
Mario CazzolaRespiratory Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Francesco BlasiDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute exacerbations are a leading cause of worsening COPD in terms of lung function decline, quality of life, and survival. They also have a relevant economic burden on the health care system. Determining the risk factors for acute exacerbation and early relapse could be a crucial element for a better management of COPD patients. This review analyzes the current knowledge and underlines the main risk factors for recurrent acute exacerbations. Comprehensive evaluation of COPD patients during stable phase and exacerbation could contribute to prevent treatment failure and relapses.

Indexed as

Anti-Bacterial AgentsBacterial InfectionsBiomarkersComorbidityDisease ProgressionHumansLungPatient Reported Outcome MeasuresPredictive Value of TestsPulmonary Disease, Chronic ObstructiveRecurrenceRespiratory Tract InfectionsRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsAnti-Bacterial AgentsBiomarkersCOPDexacerbationsinfectionspreventiontreatment

Identifiers

PMID28932112
PMCPMC5598966

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.