Evidence map›Paper›PMID 28932092›Full record

SynthesisWorld journal of gastroenterology2017

Systematic review and meta-analysis of colon cleansing preparations in patients with inflammatory bowel disease.

Sophie Restellini, Omar Kherad, Talat Bessissow, Charles Ménard, Myriam Martel, Maryam Taheri Tanjani, Peter L Lakatos, Alan N Barkun

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Sophie RestelliniDivision of Gastroenterology, Department of Medicine, McGill University Health Center, Montreal, QC H3G1A4, Canada.
Omar KheradDivision of Internal Medicine, Department of Medicine, La Tour Hospital and University of Geneva, 1217 Geneva, Switzerland.
Talat BessissowDivision of Gastroenterology, Department of Medicine, McGill University Health Center, Montreal, QC H3G1A4, Canada.
Charles MénardDivision of Gastroenterology, Department of Medicine, University of Sherbrooke, Sherbrooke, QC J1K2R1, Canada.
Myriam MartelDepartment of Clinical Epidemiology, McGill University and the McGill University Health Center, Montreal, QC H3G1A4, Canada.
Maryam Taheri TanjaniDepartment of Family Medicine, Queens University, Kingston, ON K7L 3G2, Canada.
Peter L LakatosDivision of Gastroenterology, Department of Medicine, McGill University Health Center, Montreal, QC H3G1A4, Canada.
Alan N BarkunDivision of Gastroenterology, Department of Medicine, McGill University Health Center, Montreal, QC H3G1A4, Canada. alan.barkun@muhc.mcgill.ca.
McGill University Health Centre · CAQueen's University · CAHealth Center · USUniversité de Sherbrooke · CAUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo performed a systematic review and meta-analysis to determine any possible differences in terms of effectiveness, safety and tolerability between existing colon-cleansing products in patients with inflammatory bowel disease.

methodsSystematic searches were performed (January 1980-September 2016) using MEDLINE, EMBASE, Scopus, CENTRAL and ISI Web of knowledge for randomized trials assessing preparations with or without adjuvants, given in split and non-split dosing, and in high (> 3 L) or low-volume (2 L or less) regimens. Bowel cleansing quality was the primary outcome. Secondary outcomes included patient willingness-to-repeat the procedure and side effects/complications.

resultsOut of 439 citations, 4 trials fulfilled our inclusion criteria (

conclusionIn inflammatory bowel disease population, PEG low-volume regimen seems not inferior to PEG high-volume to clean the colon, and yields improved willingness-to-repeat. Further additional research is urgently required to compare contemporary products in this population.

Indexed as

CatharticsClinical Trials as TopicColonColonoscopyDrug Administration ScheduleHumansInflammatory Bowel DiseasesPatient SatisfactionTreatment OutcomeCatharticsColonoscopyInflammatory bowel diseaseMeta-analysisPolyethylene glycol

Identifiers

PMID28932092
PMCPMC5583585
OpenAlexW2747121196

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.