Evidence map›Paper›PMID 28932083›Full record

ArticleWorld journal of gastroenterology2017

Integrating

Anastasios Ntavatzikos, Aris Spathis, Paul Patapis, Nikolaos Machairas, George Peros, Stefanos Konstantoudakis, Danai Leventakou, Ioannis G Panayiotides, Petros Karakitsos, Anna Koumarianou

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Anastasios NtavatzikosHematology-Oncology Unit, 4 Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, "ATTIKON" University Hospital, 12462 Athens, Greece. dmaal2@yahoo.gr.
Aris SpathisDepartment of Cytopathology, National and Kapodistrian University of Athens, Medical School, "ATTIKON" University Hospital, 12462 Athens, Greece.
Paul Patapis3 Department of Surgery, Medical School, National and Kapodistrian University of Athens, "ATTIKON" University Hospital, 12462 Athens, Greece.
Nikolaos Machairas3 Department of Surgery, Medical School, National and Kapodistrian University of Athens, "ATTIKON" University Hospital, 12462 Athens, Greece.
George PerosDepartment of Surgery, Medical School, National and Kapodistrian University of Athens, Evgenideio Therapeutirio S.A., "I AGIA TRIAS", 11528 Athens, Greece.
Stefanos Konstantoudakis2 Department of Pathology, University of Athens, Medical School, "ATTIKON" University Hospital, 12462 Athens, Greece.
Danai LeventakouDepartment of Cytopathology, National and Kapodistrian University of Athens, Medical School, "ATTIKON" University Hospital, 12462 Athens, Greece.
Ioannis G Panayiotides2 Department of Pathology, University of Athens, Medical School, "ATTIKON" University Hospital, 12462 Athens, Greece.
Petros KarakitsosDepartment of Cytopathology, National and Kapodistrian University of Athens, Medical School, "ATTIKON" University Hospital, 12462 Athens, Greece.
Anna KoumarianouHematology-Oncology Unit, 4 Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, "ATTIKON" University Hospital, 12462 Athens, Greece.
National and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the impact of thymidylate synthase (

methodsClinical data were collected retrospectively from records of consecutive patients with mCRC treated with fluoropyrimidine-based chemotherapy from 1/2005 to 1/2007. Formalin-fixed paraffin-embedded tissues were retrieved for analysis.

resultsThe analysis recovered 89 patients with mCRC (46.1%

conclusionThe

Indexed as

3' Untranslated RegionsAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorColorectal NeoplasmsDisease-Free SurvivalDisease ProgressionDrug Resistance, NeoplasmFemaleFollow-Up StudiesGenetic TestingHumansMaleMiddle Aged3' Untranslated RegionsBiomarkers, TumorBRAF protein, humanKRAS protein, humanProto-Oncogene Proteins B-rafProto-Oncogene Proteins p21(ras)Thymidylate SynthaseTYMS protein, humanBRAFChemotherapyKRASLoss of heterozygositymCRCPolymorphismsSurvivalThymidylate synthaseTYMS

Identifiers

PMID28932083
PMCPMC5583576
OpenAlexW2749315192

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.