Evidence map›Paper›PMID 28931860›Full record

ArticleScientific reports2017

Towards an ultra-rapid smartphone- connected test for infectious diseases.

Valérian Turbé, Eleanor R Gray, Victoria E Lawson, Eleni Nastouli, Jennifer C Brookes, Robin A Weiss, Deenan Pillay, Vincent C Emery, C Theo Verrips, Hiromi Yatsuda and 2 more

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Virus Detection: From State-of-the-Art Laboratories to Smartphone-Based Point-of-Care Testing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Microfluidic Point-of-Care Testing: Commercial Landscape and Future Directions.Frontiers in bioengineering and biotechnology · 2020
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Mobile Microfluidics.Bioengineering (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 4 countries.

Valérian TurbéLondon Centre for Nanotechnology, Faculty of Maths and Physical Sciences, University College London, 17-19, Gordon Street, London, WC1H 0AH, UK.
Eleanor R GrayLondon Centre for Nanotechnology, Faculty of Maths and Physical Sciences, University College London, 17-19, Gordon Street, London, WC1H 0AH, UK.ORCID 0000-0002-6515-839X
Victoria E LawsonOJ-Bio, International Centre for Life, Times Square, Newcastle-upon-Tyne, NE1 4EP, UK.
Eleni NastouliDepartment of Clinical Virology, University College London NHS Foundation Trust, London, W1T 4EU, UK.
Jennifer C BrookesLondon Centre for Nanotechnology, Faculty of Maths and Physical Sciences, University College London, 17-19, Gordon Street, London, WC1H 0AH, UK.
Robin A WeissDivision of Infection and Immunity, University College London, London, WC1E 6BT, UK.
Deenan PillayDivision of Infection and Immunity, University College London, London, WC1E 6BT, UK.
Vincent C EmeryDepartment of Microbial and Cellular Sciences, University of Surrey, Guildford, Surrey, GU2 7HE, UK.ORCID 0000-0001-5893-9756
C Theo VerripsQVQ Holding B.V., Utrecht, The Netherlands.
Hiromi YatsudaJapan Radio Co. Ltd., Saitama, 356-8510, Japan.
Dale AtheyOJ-Bio, International Centre for Life, Times Square, Newcastle-upon-Tyne, NE1 4EP, UK.
Rachel A McKendryLondon Centre for Nanotechnology, Faculty of Maths and Physical Sciences, University College London, 17-19, Gordon Street, London, WC1H 0AH, UK. r.a.mckendry@ucl.ac.uk.
London Centre for Nanotechnology · GBCentre for Life · GBAfrica Health Research Institute · ZAQserve Group (Netherlands) · NLUniversity College London · GBUniversity College London Hospitals NHS Foundation Trust · GBUniversity of Surrey · GB

Funding

Department of Health II-LA-1111-20004
6 · The paper itself

Abstract

The development is reported of an ultra-rapid, point-of-care diagnostic device which harnesses surface acoustic wave (SAW) biochips, to detect HIV in a finger prick of blood within 10 seconds (sample-in-result-out). The disposable quartz biochip, based on microelectronic components found in every consumer smartphone, is extremely fast because no complex labelling, amplification or wash steps are needed. A pocket-sized control box reads out the SAW signal and displays results electronically. High analytical sensitivity and specificity are found with model and real patient blood samples. The findings presented here open up the potential of consumer electronics to cut lengthy test waiting times, giving patients on the spot access to potentially life-saving treatment and supporting more timely public health interventions to prevent disease transmission.

Indexed as

Point-of-Care SystemsSmartphoneBiosensing TechniquesHIV InfectionsHumansSensitivity and SpecificityTime

Identifiers

PMID28931860
PMCPMC5607310
OpenAlexW2753957105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.