Evidence map›Paper›PMID 28931856›Full record

Observational studyScientific reports2017

Complications following vaginal mesh procedures for stress urinary incontinence: an 8 year study of 92,246 women.

Kim Keltie, Sohier Elneil, Ashwani Monga, Hannah Patrick, John Powell, Bruce Campbell, Andrew J Sims

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 6 pooled it
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 6 syntheses or guidelines pooled it, 156 citations in OpenAlex.

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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Kim KeltieNewcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Sohier ElneilUniversity College London Hospitals NHS Foundation Trust, London, UK.
Ashwani MongaUniversity Hospital of Southampton NHS Foundation Trust, Southampton, UK.
Hannah PatrickNational Institute for Health and Care Excellence, London, UK.
John PowellNational Institute for Health and Care Excellence, London, UK.
Bruce CampbellUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Andrew J SimsNewcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK. andrew.sims@nuth.nhs.uk.ORCID 0000-0002-9553-7278
National Institute for Health and Care Excellence · GBNewcastle upon Tyne Hospitals NHS Foundation Trust · GBUniversity College London Hospitals NHS Foundation Trust · GBUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Exeter · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Complications of surgical mesh procedures have led to legal cases against manufacturers worldwide and to national inquiries about their safety. The aim of this study was to investigate the rate of adverse events of these procedures for stress urinary incontinence in England over 8 years. This was a retrospective cohort study of first-time tension-free vaginal tape (TVT), trans-obturator tape (TOT) or suprapubic sling (SS) surgical mesh procedures between April 2007 and March 2015. Cases were identified from the Hospital Episode Statistics database. Outcomes included number and type of procedures, including those potentially confounded by concomitant procedures, and frequency, nature and timing of complications. 92,246 first-time surgical mesh procedures (56,648 TVT, 34,704 TOT, 834 SS and 60 combinations) were identified, including 68,002 unconfounded procedures. Peri-procedural and 30-day complication rates in the unconfounded cohort were 2.4 [2.3-2.5]% and 1.7 [1.6-1.8]% respectively; 5.9 [5.7-6.1]% were readmitted at least once within 5 years for further mesh intervention or symptoms of complications, the highest risk being within the first 2 years. Complication rates were higher in the potentially confounded cohort. The complication rate within 5 years of the mesh procedure was 9.8 [9.6:10.0]% This evidence can inform future decision-making on this procedure.

Indexed as

AdultFemaleHumansMiddle AgedOutcome Assessment, Health CarePostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk FactorsSuburethral SlingsSurgical MeshUrinary Incontinence, StressUrologic Surgical ProceduresVagina

Identifiers

PMID28931856
PMCPMC5607307
OpenAlexW2755534705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.