ArticleScientific reports2017
Cerebellar anatomical alterations and attention to eyes in autism.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Brain-based sex differences in autism spectrum disorder across the lifespan: A systematic review of structural MRI, fMRI, and DTI findings.NeuroImage. Clinical · 2021Pooled it
- Sex/gender differences in the human autistic brains: A systematic review of 20 years of neuroimaging research.NeuroImage. Clinical · 2021Pooled it
- The Cerebellum in Frontotemporal Dementia: a Meta-Analysis of Neuroimaging Studies.Neuropsychology review · 2019Pooled it
- Increased Accuracy of Emotion Recognition in Individuals with Autism-Like Traits after Five Days of Magnetic Stimulations.Neural plasticity · 2020Trial
- Eye Movements During Sentence Processing in High-functioning Autistic Children Compared to Neurotypical Peers: An Eye Tracking Study.Basic and clinical neuroscience · 2025Article
- Mapping brain function underlying naturalistic motor observation and imitation using high-density diffuse optical tomography.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Behavioral decline in Shank3Molecular autism · 2024Article
- Roles of KCNA2 in Neurological Diseases: from Physiology to Pathology.Molecular neurobiology · 2024Review
- Behavioral regression in shank3Research square · 2024Article
- Cerebellum and social abilities: A structural and functional connectivity study in a transdiagnostic sample.Human brain mapping · 2024Article
- Impaired effective functional connectivity in the social preference of children with autism spectrum disorder.Frontiers in neuroscience · 2024Article
- Understanding the relationship between cerebellar structure and social abilities.Molecular autism · 2023Article
- Brain functional connectivity mirrors genetic pleiotropy in psychiatric conditions.Brain : a journal of neurology · 2023Article
- Cerebellar Structural Abnormality in Autism Spectrum Disorder: A Magnetic Resonance Imaging Study.Psychiatry investigation · 2023Article
- Cerebellum and neurodevelopmental disorders: RORα is a unifying force.Frontiers in cellular neuroscience · 2023Article
- Deficits in cerebellum-dependent learning and cerebellar morphology in male and female BTBR autism model mice.NeuroSci · 2022Article
- CHARGE syndrome protein CHD7 regulates epigenomic activation of enhancers in granule cell precursors and gyrification of the cerebellum.Nature communications · 2021Article
- A Data Driven Approach Reveals That Anomalous Motor System Connectivity is Associated With the Severity of Core Autism Symptoms.Autism research : official journal of the International Society for Autism Research · 2021Article
- Dysregulation of Neuronal Nicotinic Acetylcholine Receptor-Cholesterol Crosstalk in Autism Spectrum Disorder.Frontiers in molecular neuroscience · 2021Article
- Automatic cerebellum anatomical parcellation using U-Net with locally constrained optimization.NeuroImage · 2020Article
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Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cerebellum is implicated in social cognition and is likely to be involved in the pathophysiology of autism spectrum disorder (ASD). The goal of our study was to explore cerebellar morphology in adults with ASD and its relationship to eye contact, as measured by fixation time allocated on the eye region using an eye-tracking device. Two-hundred ninety-four subjects with ASD and controls were included in our study and underwent a structural magnetic resonance imaging scan. Global segmentation and cortical parcellation of the cerebellum were performed. A sub-sample of 59 subjects underwent an eye tracking protocol in order to measure the fixation time allocated to the eye region. We did not observe any difference in global cerebellar volumes between ASD patients and controls; however, regional analyses found a decrease of the volume of the right anterior cerebellum in subjects with ASD compared to controls. There were significant correlations between fixation time on eyes and the volumes of the vermis and Crus I. Our results suggest that cerebellar morphology may be related to eye avoidance and reduced social attention. Eye tracking may be a promising neuro-anatomically based stratifying biomarker of ASD.
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