Evidence map›Paper›PMID 28931725›Full record

ReviewBioscience reports2017

YAP/TAZ-mediated activation of serine metabolism and methylation regulation is critical for LKB1-deficient breast cancer progression.

Qi Wu, Juanjuan Li, Si Sun, Xinyue Chen, Hanpu Zhang, Bei Li, Shengrong Sun

Open access · goldAbstract readReview
In one paragraph

Review in Bioscience reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. DNA Methylation in the Adaptive Response to Exercise.Sports medicine (Auckland, N.Z.) · 2024
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Targeting Transcription Factors in Cancer: From "Undruggable" to "Druggable".Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  15. Dietary regulation in health and disease.Signal transduction and targeted therapy · 2022
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Methylation multiplicity and its clinical values in cancer.Expert reviews in molecular medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qi WuDepartment of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P. R. China.
Juanjuan LiDepartment of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P. R. China.
Si SunDepartment of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan, Hubei, P. R. China.
Xinyue ChenDepartment of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P. R. China.
Hanpu ZhangDepartment of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P. R. China.
Bei LiDepartment of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P. R. China.
Shengrong SunDepartment of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, P. R. China sun137@sina.com.
Renmin Hospital of Wuhan University · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The crucial interplay between metabolic remodeling and the epigenetics could contribute to promote cancer progression. A remarkable association within interaction, LKB1 has been reported, suggesting that the expression of key enzymes involving

Indexed as

Adaptor Proteins, Signal TransducingAMP-Activated Protein Kinase KinasesBreast NeoplasmsDisease ProgressionDNA-Binding ProteinsDNA (Cytosine-5-)-Methyltransferase 1DNA MethylationFemaleHistocompatibility AntigensHistone-Lysine N-MethyltransferaseHumansNuclear ProteinsPhosphoproteinsProtein Serine-Threonine KinasesProto-Oncogene Proteins c-mycSerineAdaptor Proteins, Signal TransducingAMP-Activated Protein Kinase KinasesDNA-Binding ProteinsDNA (Cytosine-5-)-Methyltransferase 1DNMT1 protein, humanEHMT2 protein, humanHistocompatibility AntigensHistone-Lysine N-MethyltransferaseMYC protein, humanNuclear ProteinsPhosphoproteinsProtein Serine-Threonine KinasesProto-Oncogene Proteins c-mycSerineSTK11 protein, humanTEAD1 protein, humanTEA Domain Transcription FactorsTranscription FactorsYAP1 protein, humanYAP-Signaling Proteinsbreast cancerhistone methylationLKB1serine biosynthesisYAP/TAZ

Identifiers

PMID28931725
PMCPMC5653917
OpenAlexW2755496433

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.