Evidence map›Paper›PMID 28931681›Full record

ArticleJournal of virology2017

Insights into the Impact of CD8

Brittany Rife Magalis, David J Nolan, Patrick Autissier, Tricia H Burdo, Kenneth C Williams, Marco Salemi

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Brittany Rife MagalisEmerging Pathogens Institute and Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, Florida, USA.
David J NolanEmerging Pathogens Institute and Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, Florida, USA.
Patrick AutissierDepartment of Biology, Boston College, Chestnut Hill, Massachusetts, USA.
Tricia H BurdoDepartment of Neuroscience, Temple University, Philadelphia, Pennsylvania, USA.
Kenneth C WilliamsDepartment of Biology, Boston College, Chestnut Hill, Massachusetts, USA.
Marco SalemiEmerging Pathogens Institute and Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, Florida, USA salemi@pathology.ufl.edu.
University of Florida · USBoston College · USTemple University · US

Funding

Nonhuman Primate Reagent ResourceU24AI126683 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Diogo Magnani · 2016 to 2026
$20.1M
MONOCYTE TRAFFIC AND THE NEUROPATHOGENESIS OF AIDSR01NS040237 · NINDS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Robert Blair, Woong-Ki Kim · 1999 to 2026
$11.4M
Viral evolution in peropheral macrophages and brain during progression to AIDSR01NS063897 · NINDS · UNIVERSITY OF FLORIDA · PI SALEMI, MARCO · 2009 to 2021
$7.0M
Resource for Nonhuman Primate Cell Depleting AntibodiesR24OD010976 · OD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ENGELMAN, KATHLEEN, MAGNANI, DIOGO · 2012 to 2019
$4.7M
Intra-Host Phylogeography and Population Dynamics of SIV in the Rhesus Macaque Model of NeuroAIDSF31MH109398 · NIMH · UNIVERSITY OF FLORIDA · PI MAGALIS, BRITTANY · 2016 to 2016
$37k
NIAID NIH HHS U24 AI126683NIH HHS R24 OD010976NIMH NIH HHS F31 MH109398NINDS NIH HHS R01 NS040237NINDS NIH HHS R01 NS063897
6 · The paper itself

Abstract

A thorough understanding of the role of human immunodeficiency virus (HIV) intrahost evolution in AIDS pathogenesis has been limited by the need for longitudinally sampled viral sequences from the vast target space within the host, which are often difficult to obtain from human subjects. CD8

Indexed as

Evolution, MolecularImmunomodulationAcquired Immunodeficiency SyndromeAnimalsCD8-Positive T-LymphocytesDisease ProgressionHumansLymphocyte DepletionMacacaMembrane GlycoproteinsModels, AnimalPhylogenySequence Analysis, DNASimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusViral Envelope Proteinsgp120 protein, Simian immunodeficiency virusMembrane GlycoproteinsViral Envelope ProteinsAIDSevolutionHIVphylodynamicsSIVtissue

Identifiers

PMID28931681
PMCPMC5686727
OpenAlexW2754628626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.