Evidence map›Paper›PMID 28931634›Full record

ArticleJournal of the Royal Society, Interface2017

Improved prediction accuracy for disease risk mapping using Gaussian process stacked generalization.

Samir Bhatt, Ewan Cameron, Seth R Flaxman, Daniel J Weiss, David L Smith, Peter W Gething

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  7. Climate Change and Malaria: A Call for Robust Analytics.medRxiv : the preprint server for health sciences · 2025
    Article
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  14. PredictingFrontiers in microbiology · 2023
    Article
  15. Article
  16. Article
  17. Gaussian process forecastsEcology and evolution · 2022
    Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samir BhattDepartment of Infectious Disease Epidemiology, Imperial College London, London W2 1PG, UK bhattsamir@gmail.com.ORCID 0000-0002-0891-4611
Ewan CameronOxford Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.
Seth R FlaxmanDepartment of Statistics, University of Oxford, 24-29 St Giles, Oxford OX1 3LB, UK.
Daniel J WeissOxford Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.
David L SmithInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA 98121, USA.
Peter W GethingOxford Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK.

Funding

Transmission ProjectU19AI089674 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Isaac Ssewanyana · 2010 to 2026
$29.3M
Medical Research Council K00669XMedical Research Council MR/K00669X/1NIAID NIH HHS U19 AI089674
6 · The paper itself

Abstract

Maps of infectious disease-charting spatial variations in the force of infection, degree of endemicity and the burden on human health-provide an essential evidence base to support planning towards global health targets. Contemporary disease mapping efforts have embraced statistical modelling approaches to properly acknowledge uncertainties in both the available measurements and their spatial interpolation. The most common such approach is Gaussian process regression, a mathematical framework composed of two components: a mean function harnessing the predictive power of multiple independent variables, and a covariance function yielding spatio-temporal shrinkage against residual variation from the mean. Though many techniques have been developed to improve the flexibility and fitting of the covariance function, models for the mean function have typically been restricted to simple linear terms. For infectious diseases, known to be driven by complex interactions between environmental and socio-economic factors, improved modelling of the mean function can greatly boost predictive power. Here, we present an ensemble approach based on stacked generalization that allows for multiple nonlinear algorithmic mean functions to be jointly embedded within the Gaussian process framework. We apply this method to mapping

Indexed as

Models, BiologicalPlasmodium falciparumAfrica South of the SaharaAnimalsHumansMalaria, FalciparumPrevalencedisease mappingGaussian processmalariastacked generalization

Identifiers

PMID28931634
PMCPMC5636278

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.