Evidence map›Paper›PMID 28931605›Full record

ArticleThe Journal of biological chemistry2017

Structural basis for clonal diversity of the human T-cell response to a dominant influenza virus epitope.

Xinbo Yang, Guobing Chen, Nan-Ping Weng, Roy A Mariuzza

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  7. Thioamide Analogues of MHC I Antigen Peptides.Journal of the American Chemical Society · 2023
    Article
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  15. TCR Recognition of Peptide-MHC-I: Rule Makers and Breakers.International journal of molecular sciences · 2020
    Review
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Xinbo YangFrom the University of Maryland Institute for Bioscience and Biotechnology Research, W. M. Keck Laboratory for Structural Biology, Rockville, Maryland 20850.
Guobing Chenthe Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224.
Nan-Ping Wengthe Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224.
Roy A MariuzzaFrom the University of Maryland Institute for Bioscience and Biotechnology Research, W. M. Keck Laboratory for Structural Biology, Rockville, Maryland 20850, rmariuzz@umd.edu.
National Institute on Aging · USUniversity of Maryland, College Park · US

Funding

TCR repertoire: size, diversity, and functionZIAAG000499 · NIA · NATIONAL INSTITUTE ON AGING · PI WENG, NAN-PING PETER · 2017 to 2025
$3.6M
STRUCTURE AND FUNCTION OF T CELL ANTIGEN RECEPTORSR37AI036900 · NIAID · UNIVERSITY OF MD BIOTECHNOLOGY INSTITUTE · PI MARIUZZA, ROY A · 2000 to 2009
$3.2M
STRUCTURE AND FUNCTION OF T CELL ANTIGEN RECEPTORSR01AI036900 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI MARIUZZA, ROY A · 1995 to 2014
$1.8M
NIAID NIH HHS R01 AI036900NIAID NIH HHS R37 AI036900
6 · The paper itself

Abstract

Influenza A virus (IAV) causes an acute infection in humans that is normally eliminated by CD8

Indexed as

Models, MolecularAmino Acid SubstitutionAntibody AffinityAntibody DiversityAntigen-Antibody ComplexAntigens, ViralClonal DeletionEpitopes, T-LymphocyteHLA-A2 AntigenHumansHydrogen BondingImmunodominant EpitopesInfluenza A virusMutationPeptide FragmentsProtein ConformationAntigen-Antibody ComplexAntigens, ViralEpitopes, T-LymphocyteHLA-A2 AntigenImmunodominant Epitopesinfluenza matrix peptide (58-66)M1 protein, Influenza A virusPeptide FragmentsReceptors, Antigen, T-Cell, alpha-betaRecombinant ProteinsViral Matrix Proteinscrystal structureepitopeinfluenza virusmajor histocompatibility complex (MHC)protein complexsurface plasmon resonance (SPR)T-cell receptor

Identifiers

PMID28931605
PMCPMC5683187
OpenAlexW2756209412

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.