ArticleHeart (British Cardiac Society)2017
Sex differences in risk factor management of coronary heart disease across three regions.
Article in Heart (British Cardiac Society), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.
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Who cites it
64 citing papers in PubMed, 1 synthesis or guideline pooled it, 148 citations in OpenAlex.
- Sex Differences in Cardiovascular Medication Prescription in Primary Care: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2020Pooled it
- Cardiometabolic Risk Factors and Incident Cardiovascular Disease Events in Women vs Men With Type 1 Diabetes.JAMA network open · 2022Trial
- Sex associations and computed tomography coronary angiography-guided management in patients with stable chest pain.European heart journal · 2020Trial
- Sex-based differences in cardiovascular risk management and abdominal aortic aneurysm growth: Insights from a contemporary cohort study.Atherosclerosis · 2026Article
- Diabetic Cardiovascular Complications in Women and Young Adults.Current epidemiology reports · 2026Review
- Sex differences in mortality after percutaneous coronary intervention: a contemporary nationwide registry and prospective cohort analysis.Annals of translational medicine · 2025Article
- DNA Methylation Algorithms of Aging and Incident Cardiovascular Disease: A Prospective Cohort Study.Journal of the American Heart Association · 2025Article
- Sex differences in the association of physical activity with coronary heart disease incidence and mortality.Nature cardiovascular research · 2025Article
- Sex differences in the association of wearable accelerometer-derived physical activity with coronary heart disease incidence and mortality.Nature cardiovascular research · 2025Article
- Differences in cardiorespiratory fitness improvement following phase II cardiac rehabilitation program among post-coronary artery bypass grafting patients with varied risk factor profiles.Turk gogus kalp damar cerrahisi dergisi · 2025Article
- Sex-Based Risk Evaluation in Acute Coronary Events-A Study Conducted on an Eastern-European Population.Medicina (Kaunas, Lithuania) · 2025Article
- Diabetes, glycaemic traits and cardiovascular disease in females and males: Observational and Mendelian randomisation analyses in the UK Biobank.Diabetes, obesity & metabolism · 2025Observational
- Associations of DNA Methylation Algorithms of Aging With Cardiovascular Disease and Mortality Risk Among US Older Adults.Journal of the American Heart Association · 2025Article
- Sex differences and trends in managing cardiovascular risk factors in primary care: a dynamic cohort study.BJGP open · 2025Article
- Exploring sex-based differences in patient outcomes: A secondary analysis of Heartwatch, an Irish cardiovascular secondary prevention programme.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Review
- Lipid Lowering Therapy Utilization and Lipid Goal Attainment in Women.Current atherosclerosis reports · 2025Review
- Demographic Predictors of Elevated LDL Cholesterol in Type 1 Diabetes: A Cross-Sectional Study.Clinical diabetes : a publication of the American Diabetes Association · 2025Article
- Article
- Trends in avoidable mortality from cardiovascular diseases in the European Union, 1995-2020: a retrospective secondary data analysis.The Lancet regional health. Europe · 2024Article
4 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 7 institutions in 6 countries.
Funding
Abstract
objectiveTo investigate whether there are sex differences in risk factor management of patients with established coronary heart disease (CHD), and to assess demographic variations of any potential sex differences.
methodsPatients with CHD were recruited from Europe, Asia, and the Middle East between 2012-2013. Adherence to guideline-recommended treatment and lifestyle targets was assessed and summarised as a Cardiovascular Health Index Score (CHIS). Age-adjusted regression models were used to estimate odds ratios for women versus men in risk factor management.
results10 112 patients (29% women) were included. Compared with men, women were less likely to achieve targets for total cholesterol (OR 0.50, 95% CI 0.43 to 0.59), low-density lipoprotein cholesterol (OR 0.57, 95% CI 0.51 to 0.64), and glucose (OR 0.78, 95% CI 0.70 to 0.87), or to be physically active (OR 0.74, 95% CI 0.68 to 0.81) or non-obese (OR 0.82, 95% CI 0.74 to 0.90). In contrast, women had better control of blood pressure (OR 1.31, 95% CI 1.20 to 1.44) and were more likely to be a non-smoker (OR 1.93, 95% CI 1.67 to 2.22) than men. Overall, women were less likely than men to achieve all treatment targets (OR 0.75, 95% CI 0.60 to 0.93) or obtain an adequate CHIS (OR 0.81, 95% CI 0.73 to 0.91), but no significant differences were found for all lifestyle targets (OR 0.93, 95% CI 0.84 to 1.02). Sex disparities in reaching treatment targets were smaller in Europe than in Asia and the Middle East. Women in Asia were more likely than men to reach lifestyle targets, with opposing results in Europe and the Middle East.
conclusionsRisk factor management for the secondary prevention of CHD was generally worse in women than in men. The magnitude and direction of the sex differences varied by region.
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