ArticleDiabetes care2018
Cumulative Kidney Complication Risk by 50 Years of Type 1 Diabetes: The Effects of Sex, Age, and Calendar Year at Onset.
Article in Diabetes care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
59 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.
- Sex-specific association between type 1 diabetes and the risk of end-stage renal disease: a systematic review and meta-analysis.Endocrine · 2020Pooled it
- Effect of Finerenone on Albuminuria in Type 1 Diabetes by Baseline HbA1c Level and Diabetes Duration: An Exploratory Analysis of the FINE-ONE Trial.Diabetes care · 2026Trial
- Adjunct-to-insulin therapy using SGLT2 inhibitors in youth with type 1 diabetes: a randomized controlled trial.Nature medicine · 2025Trial
- Optimal Frequency of Urinary Albumin Screening in Type 1 Diabetes.Diabetes care · 2022Trial
- Serum Urate Lowering with Allopurinol and Kidney Function in Type 1 Diabetes.The New England journal of medicine · 2020Trial
- Differential Oral Absorption Pharmacokinetics of Tacrolimus in Simultaneous Kidney-Pancreas Transplant Compared to Kidney Transplant Recipients.Clinical pharmacokinetics · 2026Observational
- Clinical modifiers of the association between type 1 diabetes and dementia incidence.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Trajectory of Kidney Function in T1D over Time: A Scoping Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026Review
- Finerenone in type 1 diabetes and chronic kidney disease: short-term efficacy and safety insights.International urology and nephrology · 2026Article
- Characteristics of above 65-year-olds with type 1 diabetes in the Finnish diabetic nephropathy study.Acta diabetologica · 2026Observational
- Impact of onset age of type 2 diabetes mellitus on risk of renal complications compared to age-matched non-diabetic patients: Two cohort studies in the United Kingdom and Hong Kong.Diabetes, obesity & metabolism · 2025Article
- The Changing Epidemiology of Type 1 Diabetes: A Global Perspective.Diabetes, obesity & metabolism · 2025Review
- Cost-effectiveness analysis model for sotagliflozin compared with insulin monotherapy for patients with type 1 diabetes and chronic kidney disease.Journal of managed care & specialty pharmacy · 2025Article
- A Cross-Tissue Transcriptome-Wide Association Study Reveals Novel Susceptibility Genes for Diabetic Kidney Disease in the FinnGen Cohort.Biomedicines · 2025Article
- Glycemic Variability and Its Association with Traditional Glycemic Control Biomarkers in Patients with Type 1 Diabetes: A Cross-Sectional, Multicenter Study.Journal of clinical medicine · 2025Article
- Comparison of GFR estimation in patients with diabetes mellitus using the EKFC and CKD-EPI equations.Journal of nephrology · 2025Article
- Exploring the Incidence and Risk Factors of Diabetic Nephropathy in Type 1 Diabetes: Insights from a Retrospective Cohort Study in Northwest China.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Prognosis for Type 1 Diabetes with Diabetic Nephropathy between 2000 and 2020 - Changes in Kidney Function Decline Over Time and Development of Cardiovascular Disease, Kidney Failure, and Mortality.Kidney international reports · 2024Article
- Article
- Major adverse events in youth-onset type 1 and type 2 diabetes: The SEARCH and TODAY studies.Diabetes research and clinical practice · 2024Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
objectiveA common belief is that only a minority of patients with type 1 diabetes (T1D) develop advanced kidney disease and that incidence is higher among men and lower in those diagnosed at a younger age. However, because few patients with T1D survived to older ages until recently, long-term risks have been unclear. RESEARCH DESIGN AND
methodsWe examined the 50-year cumulative kidney complication risk in a childhood-onset T1D cohort diagnosed during 1950-80 (
resultsBy 50 years
conclusionsSome degree of kidney disease in T1D is virtually universal at long durations and not declining, which has major implications for formulating health care and research strategies. ESRD has declined, but continues to affect >25% of the population by 40 years
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.