Evidence map›Paper›PMID 28931433›Full record

ReviewMolecular brain2017

Role of GABA

Richard W Olsen, Jing Liang

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Molecular brain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06634771 (Frontal E/I Balance Mediation of tACS Effects on Behavioral Flexibility), which is not on this map. Cited by 66 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06634771 naterminatednot on this mapstarted 2024, after this paper: background citation

Frontal E/I Balance Mediation of tACS Effects on Behavioral Flexibility

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2024 to 2025Enrolled7ConditionsBehavioral Flexibility, Healthy Volunteers, High Risk Alcohol UseArms10 Hz transcranial alternating current stimulation (tACS), sham transcranial alternating current stimulation (tACS)
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 1 synthesis or guideline pooled it, 114 citations in OpenAlex.

  1. Potential TMS biomarkers for GABAAlcohol, clinical & experimental research · 2025
    Pooled it
  2. Review
  3. Assessment of GABANeuroscience letters · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. The influence of drug class on reward in substance use disorders.Pharmacology, biochemistry, and behavior · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Interspecies and regional variability of alcohol action on large cerebral arteries: regulation by KCNMB1 proteins.American journal of physiology. Regulatory, integrative and comparative physiology · 2023
    Article
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Richard W OlsenDepartment of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USA. rolsen@mednet.ucla.edu.
Jing LiangDepartment of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USA.
University of California, Los Angeles · USUniversity of Southern California · US

Funding

Unique pharmacology of ligand sites on delta subunit-containing GABA-A receptorsR01AA021213 · NIAAA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI OLSEN, RICHARD W, WALLNER, MARTIN · 2013 to 2019
$1.6M
NIAAA NIH HHS R01 AA021213
6 · The paper itself

Abstract

GABAergic inhibitory transmission is involved in the acute and chronic effects of ethanol on the brain and behavior. One-dose ethanol exposure induces transient plastic changes in GABA

Indexed as

AlcoholismAnimalsDisease Models, AnimalEthanolHumansModels, BiologicalReceptors, GABA-ARodentiaEthanolReceptors, GABA-AChronic intermittent ethanolGABAA receptorsInhibitory synaptic plasticityRodent model of alcoholism

Identifiers

PMID28931433
PMCPMC5605989
OpenAlexW2755828547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.