Evidence map›Paper›PMID 28930992›Full record

ArticleJournal of visualized experiments : JoVE2017

A Cell Culture Model of Resistance Arteries.

Lauren A Biwer, Christophe Lechauve, Sheri Vanhoose, Mitchell J Weiss, Brant E Isakson

Open access · hybridAbstract readVideo-Audio Media
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of visualized experiments : JoVE, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Functional Interaction among KInternational journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lauren A BiwerDepartment of Molecular Physiology and Biophysics, University of Virginia School of Medicine; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine.
Christophe LechauveDepartment of Hematology, St. Jude Children's Research Hospital.
Sheri VanhooseResearch Histology Core, University of Virginia School of Medicine.
Mitchell J WeissDepartment of Hematology, St. Jude Children's Research Hospital.
Brant E IsaksonDepartment of Molecular Physiology and Biophysics, University of Virginia School of Medicine; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine; Brant@virginia.edu.
University of Virginia · USSt. Jude Children's Research Hospital · US

Funding

BASIC CARDIOVASCULAR RESEARCH TRAINING GRANTT32HL007284 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Brant E Isakson, Gary K Owens · 1985 to 2026
$19.6M
Mechanisms of Heterocellular Signaling at the Myoenothelial JunctionR01HL088554 · NHLBI · UNIVERSITY OF VIRGINIA · PI ISAKSON, BRANT E, WEISS, MITCHELL J · 2008 to 2017
$3.8M
NHLBI NIH HHS R01 HL088554NHLBI NIH HHS T32 HL007284
6 · The paper itself

Abstract

The myoendothelial junction (MEJ), a unique signaling microdomain in small diameter resistance arteries, exhibits localization of specific proteins and signaling processes that can control vascular tone and blood pressure. As it is a projection from either the endothelial or smooth muscle cell, and due to its small size (on average, an area of ~1 µm

Indexed as

ArteriesCell Culture TechniquesCoculture TechniquesEndothelial CellsHumansMyocytes, Smooth MuscleVascular Resistance

Identifiers

PMID28930992
PMCPMC5752193
OpenAlexW2751463944

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.