Evidence map›Paper›PMID 28930848›Full record

Trial reportMedicine2017

Nociceptive stimulation during Macintosh direct laryngoscopy compared with McGrath Mac videolaryngoscopy: A randomized trial using indirect evaluation using an automated administration of propofol and remifentanil.

Rathvirak Ing, Ngai Liu, Thierry Chazot, Julien Fessler, Jean François Dreyfus, Marc Fischler, Morgan Le Guen

Registry-linked trialOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02245789 (Does the Use of a Videolaryngoscope Modifies Anesthetic Induction ?), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02245789 nacompletednot on this map

Does the Use of a Videolaryngoscope Modifies Anesthetic Induction ?

TypeinterventionalSponsorHopital FochRan2014 to 2015Enrolled50ConditionsTracheal IntubationArmsTracheal intubation, Propofol and remifentanil anesthesia
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Rathvirak IngDepartment of Anesthesiology and Critical Care Medicine, Avicenne University Hospital, Bobigny, France Paris-13 University, France Department of Anesthesiology, Hospital Foch, Suresnes, France University Versailles Saint-Quentin en Yvelines, France Outcomes Research Consortium, Cleveland, Ohio Bouère, France.
Ngai Liu
Thierry Chazot
Julien Fessler
Jean François Dreyfus
Marc Fischler
Morgan Le Guen
Université de Versailles Saint-Quentin-en-Yvelines · FRHôpital Foch · FROutcomes Research Consortium · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDecrease of the nociceptive stimulation induced by laryngoscopy could be an advantage for patients without risk of difficult intubation. The present study aimed to compare the difference in nociceptive stimulation between the use of a conventional laryngoscope or of a videolaryngoscope. Amount of nociception was assessed indirectly using the peak remifentanil concentration determined by a closed-loop administration of propofol and remifentanil with bispectral index (BIS) as the input signal (target 50).

methodsA prospective single-center randomized study was performed including surgical patients without predictable risk of difficult mask ventilation or of difficult tracheal intubation. Forty consecutive surgery patients were randomly assigned to CL group (conventional laryngoscope) or VL group (McGrath Mac videolaryngoscope). Induction of anesthesia was performed automatically using the closed-loop system and myorelaxation with atracurium. The allocation was revealed just before tracheal intubation. The primary outcome was the peak plasma remifentanil concentration observed during the 5-minute period which followed intubation.

resultsSixteen patients in the CL group and 11 in the VL group were analyzed. Plasmatic remifentanil and propofol concentrations were similar in both groups either before tracheal intubation or during the 5 minutes following intubation. There was a nonsignificant between-group difference (P = .09) for the peak concentration of remifentanil. A comparable result was observed for other outcomes except for the heart rate which increased in the CL group.

conclusionUse of the videolaryngoscope McGrath Mac did not reduce the nociceptive stimulation induced during intubation as evaluated by the automatically administered remifentanil concentration.

trial registrationClinicalTrials.gov, NCT02245789.

Indexed as

Video RecordingAdultAgedAnesthetics, IntravenousFemaleHumansIntubation, IntratrachealLaryngoscopyMaleMiddle AgedPainPiperidinesPropofolProspective StudiesRemifentanilAnesthetics, IntravenousPiperidinesPropofolRemifentanil

Identifiers

PMID28930848
PMCPMC5617715
OpenAlexW2754717426

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.