Evidence map›Paper›PMID 28930697›Full record

ArticleNeoplasia (New York, N.Y.)2017

Overexpression of MUC1 and Genomic Alterations in Its Network Associate with Prostate Cancer Progression.

Xiaozeng Lin, Yan Gu, Anil Kapoor, Fengxiang Wei, Tariq Aziz, Diane Ojo, Yanzhi Jiang, Michael Bonert, Bobby Shayegan, Huixiang Yang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Neoplasia (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Research progress of MUC1 in genitourinary cancers.Cellular & molecular biology letters · 2024
    Review
  5. Review
  6. Dependence on MUC1-C in Progression of Neuroendocrine Prostate Cancer.International journal of molecular sciences · 2023
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. FAM84B promotes prostate tumorigenesis through a network alteration.Therapeutic advances in medical oncology · 2019
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Xiaozeng LinDivision of Nephrology, Department of Medicine, McMaster University; Father Sean O'Sullivan Research Institute; Hamilton Center for Kidney Research, St. Joseph's Hospital.
Yan GuDivision of Nephrology, Department of Medicine, McMaster University; Father Sean O'Sullivan Research Institute; Hamilton Center for Kidney Research, St. Joseph's Hospital.
Anil KapoorFather Sean O'Sullivan Research Institute; Department of Surgery, McMaster University, Hamilton, Ontario, Canada.
Fengxiang WeiGenetics Laboratory, Longgang District Maternity and Child Healthcare Hospital, Longgang District, Shenzhen, Guangdong, PR China.
Tariq AzizDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Diane OjoDivision of Nephrology, Department of Medicine, McMaster University; Father Sean O'Sullivan Research Institute; Hamilton Center for Kidney Research, St. Joseph's Hospital.
Yanzhi JiangDivision of Nephrology, Department of Medicine, McMaster University; Father Sean O'Sullivan Research Institute; Hamilton Center for Kidney Research, St. Joseph's Hospital; Department of Gastroenterology, Xiangya Hospital, Central South University, Changsa, Hunan, PR China.
Michael BonertDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Bobby ShayeganFather Sean O'Sullivan Research Institute; Department of Surgery, McMaster University, Hamilton, Ontario, Canada.
Huixiang YangDepartment of Gastroenterology, Xiangya Hospital, Central South University, Changsa, Hunan, PR China. Electronic address: haowei727499@163.com.
Khalid Al-NedawiDivision of Nephrology, Department of Medicine, McMaster University; Father Sean O'Sullivan Research Institute; Hamilton Center for Kidney Research, St. Joseph's Hospital.
Pierre MajorDivision of Medical Oncology, Department of Oncology, McMaster University, Hamilton, Ontario, Canada. Electronic address: majorp@HHSC.ca.
Damu TangDivision of Nephrology, Department of Medicine, McMaster University; Father Sean O'Sullivan Research Institute; Hamilton Center for Kidney Research, St. Joseph's Hospital. Electronic address: damut@mcmaster.ca.
McMaster University · CASt. Joseph Hospital · USXiangya Hospital Central South University · CNShenzhen Maternity and Child Healthcare Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigate the association of MUC1 with castration-resistant prostate cancer (CRPC), bone metastasis, and PC recurrence. MUC1 expression was studied in patient-derived bone metastasis and CRPCs produced by prostate-specific PTEN

Indexed as

Gene Expression Regulation, NeoplasticAgedAged, 80 and overAnimalsBiomarkers, TumorBone NeoplasmsDisease ProgressionGene Regulatory NetworksGenomicsHumansMaleMiceMice, Inbred NODMice, KnockoutMice, SCIDMiddle AgedBiomarkers, TumorMUC1 protein, humanMucin-1

Identifiers

PMID28930697
PMCPMC5605493
OpenAlexW2754951041

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.