Evidence map›Paper›PMID 28930616›Full record

ArticleFrontiers in bioscience (Elite edition)2018

Development of a semi-automated image-based high-throughput drug screening system.

Remzi Onur Eren, Dmitry Kopelyanskiy, Dimitri Moreau, Julien Bortoli Chapalay, Marc Chambon, Gerardo Turcatti, Lon-Fye Lye, Stephen M Beverley, Nicolas Fasel

Open access · greenAbstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioscience (Elite edition), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. NN-assisted image analysis for quantifying intracellularFrontiers in cellular and infection microbiology · 2026
    Article
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  4. Frontiers in cellular and infection microbiology · 2022
    Article
  5. ImageJ for Partially and Fully Automated Analysis of Trypanosome Micrographs.Methods in molecular biology (Clifton, N.J.) · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Remzi Onur ErenDepartment of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland.
Dmitry KopelyanskiyDepartment of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland.
Dimitri MoreauAccess Platform Swiss National Centre of Competence in Research (NCCR), University of Geneva, 1211 Geneva, Switzerland.
Julien Bortoli ChapalayBiomolecular Screening Facility, Ecole Polytechnique Federale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
Marc ChambonBiomolecular Screening Facility, Ecole Polytechnique Federale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
Gerardo TurcattiBiomolecular Screening Facility, Ecole Polytechnique Federale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
Lon-Fye LyeDepartment of Molecular Microbiology, School of Medicine, Washington University, St. Louis, MO 63110, USA.
Stephen M BeverleyDepartment of Molecular Microbiology, School of Medicine, Washington University, St. Louis, MO 63110, USA.
Nicolas FaselDepartment of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland, nicolas.fasel@unil.ch.
University of Lausanne · CH

Funding

MOLECULAR GENETICS OF LEISHMANIA USING DNA TRANSFECTIONR01AI029646 · NIAID · WASHINGTON UNIVERSITY · PI BEVERLEY, STEPHEN M · 1990 to 2015
$9.3M
Leishmania RNA virus (LRV) infectivity and host responsesR56AI099364 · NIAID · WASHINGTON UNIVERSITY · PI BEVERLEY, STEPHEN M · 2013 to 2013
$493k
NIAID NIH HHS R01 AI029646NIAID NIH HHS R56 AI099364
6 · The paper itself

Abstract

We previously reported that the innate sensing of the endosymbiont

Indexed as

AutomationHigh-Throughput Screening AssaysAnimalsAntiprotozoal AgentsDrug Evaluation, PreclinicalLeishmaniaMacrophagesMiceMice, Inbred C57BLAntiprotozoal Agents

Identifiers

PMID28930616
PMCPMC5735416
OpenAlexW2760421831

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.