Evidence map›Paper›PMID 28930190›Full record

ArticleNutrients2017

Oligonol, a Low-Molecular Weight Polyphenol Derived from Lychee, Alleviates Muscle Loss in Diabetes by Suppressing Atrogin-1 and MuRF1.

Hung-Wen Liu, Yen-Ju Chen, Yun-Ching Chang, Sue-Joan Chang

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 44 citations in OpenAlex.

  1. Trial
  2. Review
  3. A Novel Blend ofFoods (Basel, Switzerland) · 2026
    Article
  4. Effects of Bioconverted Guava Leaf (International journal of molecular sciences · 2025
    Article
  5. Mitigation of high-fat diet-induced sarcopenia byFood science and biotechnology · 2025
    Article
  6. OligonolInternational journal of molecular sciences · 2024
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hung-Wen LiuDepartment of Life Sciences, National Cheng Kung University, No. 1, University Road, Tainan 701, Taiwan. hwliu@ntnu.edu.tw.
Yen-Ju ChenDepartment of Life Sciences, National Cheng Kung University, No. 1, University Road, Tainan 701, Taiwan. ohaayan@gmail.com.
Yun-Ching ChangDepartment of Life Sciences, National Cheng Kung University, No. 1, University Road, Tainan 701, Taiwan. viyanchang@gmail.com.
Sue-Joan ChangDepartment of Life Sciences, National Cheng Kung University, No. 1, University Road, Tainan 701, Taiwan. sjchang@mail.ncku.edu.tw.
National Cheng Kung University · TWNational Taiwan Normal University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stimulation of the ubiquitin-proteasome pathway-especially E3 ubiquitin ligases Atrogin-1 and MuRF1-is associated with muscle loss in diabetes. Elevated lipid metabolites impair myogenesis. Oligonol, a low molecular weight polyphenol derived from lychee, exhibited anti-diabetic and anti-obesity properties, suggesting it could be a proper supplement for attenuating muscle loss. Dietary (10 weeks) oligonol supplementation (20 or 200 mg/kg diet) on the skeletal muscle loss was investigated in diabetic

Indexed as

AnimalsCatechinCell DifferentiationCells, CulturedDiabetes Mellitus, ExperimentalDisease Models, AnimalForkhead Box Protein O3FruitGene Expression RegulationLitchiMaleMiceMice, Inbred C57BLMolecular WeightMuscle ProteinsMuscle, SkeletalCatechinFbxo32 protein, mouseForkhead Box Protein O3FoxO3 protein, mouseMuscle ProteinsNF-kappa BoligonolPhenolsPolyphenolsRNA, MessengerSirt1 protein, mouseSirtuin 1SKP Cullin F-Box Protein LigasesTrim63 protein, mouseTripartite Motif ProteinsUbiquitin-Protein LigasesAtrogin-1 and MuRF1diabetesflavanol-rich lychee fruit extractmuscle lossNF-κB

Identifiers

PMID28930190
PMCPMC5622800
OpenAlexW2755424804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.