Evidence map›Paper›PMID 28930062›Full record

ArticleJournal of studies on alcohol and drugs2017

Single Motherhood, Alcohol Dependence, and Smoking During Pregnancy: A Propensity Score Analysis.

Mary Waldron, Kathleen K Bucholz, Min Lian, Christina N Lessov-Schlaggar, Ruth Huang Miller, Michael T Lynskey, Valerie S Knopik, Pamela A F Madden, Andrew C Heath

Open access · greenAbstract read
In one paragraph

Article in Journal of studies on alcohol and drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Mary WaldronDepartment of Counseling and Educational Psychology, School of Education, Indiana University, Bloomington, Indiana.
Kathleen K BucholzMidwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Min LianDepartment of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Christina N Lessov-SchlaggarMidwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Ruth Huang MillerMidwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Michael T LynskeyAddictions Department, Institute of Psychiatry, Psychology & Neuroscience, King's College, London, England.
Valerie S KnopikDivision of Behavioral Genetics, Department of Psychiatry, Rhode Island Hospital, Providence, Rhode Island.
Pamela A F MaddenMidwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Andrew C HeathMidwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri.
Washington University in St. Louis · USBrown University · USIndiana University Bloomington · USKing's College London · GB

Funding

PILOT--GENETIC EPIDEMIOLOGY OF ALCOHOL AND TOBACCO CONSUMPTION IN CHINESE SAMPLEP50AA011998 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 1999 to 2008
$12.6M
ALCOHOLISM: GENETIC EPIDEMIOLOGIC TWIN STUDYR01AA009022 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 1994 to 2004
$3.3M
ALCOHOL USE DISORDER IN YOUNG WOMEN: GENETIC EPIDEMIOLOGY: MOAFTS WAVE 7R01AA017915 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 2009 to 2013
$3.2M
GxE in Early Childhood: Twin MothersR01HD049024 · NICHD · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 2005 to 2009
$2.9M
Prenatal tobacco exposure: effects on neuropsychological outcomes and ADHDR01DA023134 · NIDA · RHODE ISLAND HOSPITAL · PI KNOPIK, VALERIE S · 2008 to 2013
$2.7M
GENE-ENVIRONMENT INTERPLAY IN ALCOHOLISMK05AA017688 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 2008 to 2017
$1.9M
NEIGHBORHOOD, FAMILY AND INDIVIDUAL FACTORS IN ADOLESCENT DRINKINGR01AA021492 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C., SCHOOTMAN, MARIO · 2013 to 2016
$1.2M
GENE-NEIGHBORHOOD INTERACTION IN ADOLESCENT AND YOUNG ADULT SMOKINGK07CA178331 · NCI · WASHINGTON UNIVERSITY · PI LIAN, MIN · 2013 to 2017
$661k
NCI NIH HHS K07 CA178331NIAAA NIH HHS K05 AA017688NIAAA NIH HHS P50 AA011998NIAAA NIH HHS R01 AA009022NIAAA NIH HHS R01 AA017915NIAAA NIH HHS R01 AA021492NICHD NIH HHS R01 HD049024NIDA NIH HHS R01 DA023134
6 · The paper itself

Abstract

objectiveFew studies linking single motherhood and maternal smoking during pregnancy consider correlated risk from problem substance use beyond history of smoking and concurrent use of alcohol. In the present study, we used propensity score methods to examine whether the risk of smoking during pregnancy associated with single motherhood is the result of potential confounders, including alcohol dependence.

methodData were drawn from mothers participating in a birth cohort study of their female like-sex twin offspring (n = 257 African ancestry; n = 1,711 European or other ancestry). We conducted standard logistic regression models predicting smoking during pregnancy from single motherhood at twins' birth, followed by propensity score analyses comparing single-mother and two-parent families stratified by predicted probability of single motherhood.

resultsIn standard models, single motherhood predicted increased risk of smoking during pregnancy in European ancestry but not African ancestry families. In propensity score analyses, rates of smoking during pregnancy were elevated in single-mother relative to two-parent European ancestry families across much of the spectrum a priori risk of single motherhood. Among African ancestry families, within-strata comparisons of smoking during pregnancy by single-mother status were nonsignificant.

conclusionsThese findings highlight single motherhood as a unique risk factor for smoking during pregnancy in European ancestry mothers, over and above alcohol dependence. Additional research is needed to identify risks, beyond single motherhood, associated with smoking during pregnancy in African ancestry mothers.

Indexed as

AdolescentAdultAlcoholismCohort StudiesFemaleHumansMothersParentsPregnancyPregnancy ComplicationsPropensity ScoreRisk FactorsSmokingTwinsWhite PeopleYoung Adult

Identifiers

PMID28930062
PMCPMC5675425
OpenAlexW2760116993

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.