Evidence map›Paper›PMID 28930001›Full record

ArticleEmerging infectious diseases2017

Antimicrobial Drug Prescription and Neisseria gonorrhoeae Susceptibility, United States, 2005-2013.

Robert D Kirkcaldy, Monina G Bartoces, Olusegun O Soge, Stefan Riedel, Grace Kubin, Carlos Del Rio, John R Papp, Edward W Hook, Lauri A Hicks

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Robert D Kirkcaldy
Monina G Bartoces
Olusegun O Soge
Stefan Riedel
Grace Kubin
Carlos Del Rio
John R Papp
Edward W Hook
Lauri A Hicks

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated whether outpatient antimicrobial drug prescribing is associated with Neisseria gonorrhoeae antimicrobial drug susceptibility in the United States. Using susceptibility data from the Gonococcal Isolate Surveillance Project during 2005-2013 and QuintilesIMS data on outpatient cephalosporin, macrolide, and fluoroquinolone prescribing, we constructed multivariable linear mixed models for each antimicrobial agent with 1-year lagged annual prescribing per 1,000 persons as the exposure and geometric mean MIC as the outcome of interest. Multivariable models did not demonstrate associations between antimicrobial drug prescribing and N. gonorrhoeae susceptibility for any of the studied antimicrobial drugs during 2005-2013. Elucidation of epidemiologic factors contributing to resistance, including further investigation of the potential role of antimicrobial drug use, is needed.

Indexed as

Drug Resistance, Multiple, BacterialAnti-Bacterial AgentsCephalosporinsCitiesDrug PrescriptionsFluoroquinolonesGonorrheaHumansLinear ModelsMacrolidesMicrobial Sensitivity TestsMultivariate AnalysisNeisseria gonorrhoeaeUnited StatesAnti-Bacterial AgentsCephalosporinsFluoroquinolonesMacrolidesantibacterial agentsantimicrobial drugbacterialdrug resistancedrug susceptibilitygonorrheaNeisseria gonorrhoeaeUnited Statesutilization

Identifiers

PMID28930001
PMCPMC5621530

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.