Evidence map›Paper›PMID 28929350›Full record

ArticleEJNMMI research2017

Optimal MRI sequences for

Spencer T Lake, Kirsten L Greene, Antonio C Westphalen, Spencer C Behr, Ronald Zagoria, Eric J Small, Peter R Carroll, Thomas A Hope

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Frontiers in oncology · 2023
    Pooled it
  2. PET/MRI in prostate cancer: a systematic review and meta-analysis.European journal of nuclear medicine and molecular imaging · 2021
    Pooled it
  3. Pooled it
  4. Metaanalysis ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Pooled it
  5. Trial
  6. Article
  7. The Diagnostic Performance ofIranian journal of public health · 2024
    Review
  8. PET/MRI in colorectal and anal cancers: an update.Abdominal radiology (New York) · 2023
    Review
  9. International EANM-SNMMI-ISMRM consensus recommendation for PET/MRI in oncology.European journal of nuclear medicine and molecular imaging · 2023
    Article
  10. Article
  11. EJNMMI physics · 2020
    Article
  12. Summary of the First ISMRM-SNMMI Workshop on PET/MRI: Applications and Limitations.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Positron emission tomography in prostate cancer: An update on state of the art.Indian journal of urology : IJU : journal of the Urological Society of India
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Spencer T LakeDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue - 0628, San Francisco, CA, 94143-0628, USA.
Kirsten L GreeneDepartment of Urology, University of California, 1825 4th Street, 4th floor, UCSF Ron Conway Family Gateway Medical Building, San Francisco, CA, 94158, USA.
Antonio C WestphalenDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue - 0628, San Francisco, CA, 94143-0628, USA.
Spencer C BehrDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue - 0628, San Francisco, CA, 94143-0628, USA.
Ronald ZagoriaDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue - 0628, San Francisco, CA, 94143-0628, USA.
Eric J SmallUCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.
Peter R CarrollDepartment of Urology, University of California, 1825 4th Street, 4th floor, UCSF Ron Conway Family Gateway Medical Building, San Francisco, CA, 94158, USA.
Thomas A HopeDepartment of Radiology and Biomedical Imaging, University of California, 505 Parnassus Avenue - 0628, San Francisco, CA, 94143-0628, USA. thomas.hope@ucsf.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPET/MRI can be used for the detection of disease in biochemical recurrence (BCR) patients imaged with

resultsPSMA-positive foci were detected in 89.1% (49/55) of patients evaluated. Small FOV T2 performed best for lymph nodes and detected correlates for all PSMA-avid lymph nodes. DCE imaging performed the best for suspected prostate bed recurrence, detecting correlates for 87.5% (14/16) of PSMA-positive prostate bed foci. The 8-min PET acquisition performed better than the 3-min acquisition for lymph nodes smaller than 1 cm, detecting 100% (57/57) of lymph nodes less than 1 cm, compared to 78.9% (45/57) for the 3-min acquisition.

conclusionPSMA PET/MRI performed well for the detection of sites of suspected recurrent disease in patients with BCR. Of the MRI sequences obtained for localization, small FOV T2 images detected the greatest proportion of PSMA-positive abdominopelvic lymph nodes and DCE imaging detected the greatest proportion of PSMA-positive prostate bed foci. The 8-min PET acquisition was superior to the 3 min acquisition for detection of small lymph nodes.

Indexed as

Biochemical recurrencePET/MRIProstate cancerProstate-specific membrane antigenPSMA

Identifiers

PMID28929350
PMCPMC5605480

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.