ArticleTechniques in coloproctology2017
Colorectal anastomotic leak: delay in reintervention after false-negative computed tomography scan is a reason for concern.
Article in Techniques in coloproctology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Matrix metalloproteinase-9 in relation to patients with complications after colorectal surgery: a systematic review.International journal of colorectal disease · 2021Pooled it
- Hyponatremia could identify patients with intrabdominal sepsis and anastomotic leak after colorectal surgery: a systematic review of the literature.Updates in surgery · 2019Pooled it
- Trial
- Early postoperative endoscopic evaluation of rectal anastomoses: a prospective cross-sectional study.Surgical endoscopy · 2022Trial
- Article
- Serum calprotectin as a biomarker for postoperative complications in colorectal surgery: a pilot study defining normal postoperative dynamics.BMC surgery · 2025Article
- Machine Learning Models Using Post-operative CRP Trends to Predict Colorectal Anastomotic Leak: A Pilot Study.Cureus · 2025Article
- The Value of C-Reactive Protein and Peritoneal Cytokines as Early Predictors of Anastomotic Leak after Colorectal Surgery.Diagnostics (Basel, Switzerland) · 2024Article
- Is early CT in cases of elevated postoperative CRP the best option for the diagnosis of colorectal anastomotic leakage?International journal of colorectal disease · 2023Article
- CT scan for early diagnosis of anastomotic leak after colorectal surgery: is rectal contrast useful?Techniques in coloproctology · 2023Article
- Development of a warning score for early detection of colorectal anastomotic leakage: Hype or hope?World journal of gastrointestinal surgery · 2022Article
- Usefulness of serum C-reactive protein and calprotectin for the early detection of colorectal anastomotic leakage: A prospective observational study.World journal of gastroenterology · 2022Observational
- Early Diagnosis of Anastomotic Leakage After Gastric Cancer Surgery Via Analysis of Inflammatory Factors in Abdominal Drainage.Annals of surgical oncology · 2022Article
- C-reactive protein (CRP) trajectory as a predictor of anastomotic leakage after rectal cancer resection: A multicentre cohort study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022Article
- Management of Acute Anastomotic Leaks.Clinics in colon and rectal surgery · 2021Review
- The importance of rectal contrast in CT assessment to detect anastomotic leakage after colorectal surgery.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2021Article
- The Association of Coloproctology of Great Britain and Ireland consensus guidelines in emergency colorectal surgery.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2021Article
- The Usefulness of an Endoscopic OverStitch Suturing System for Managing Anastomotic Dehiscence - A Case Report.GE Portuguese journal of gastroenterology · 2020Article
- Surgical complications in colorectal cancer patients.Annals of medicine and surgery (2012) · 2020Review
- A multicentre cohort study of serum and peritoneal biomarkers to predict anastomotic leakage after rectal cancer resection.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2020Article
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6 authors.
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Abstract
backgroundEarly detection of anastomotic leakage (AL) after colorectal surgery followed by timely reintervention is of crucial importance. The aim of this study was to investigate the accuracy of computed tomography (CT) imaging for AL and the effects of delay in reintervention after a false-negative CT.
methodsAll files from patients who had colorectal surgery with primary anastomoses between 2009 and 2014 were reviewed. The predictive value of CT scanning for AL was determined and correlated with short-term postoperative patient outcomes. In addition, factors predictive of false-negative scans were assessed.
resultsSix hundred and twenty-eight patient files were reviewed. In total, a CT scan was performed in 127 patients. Overall, leakage was seen in 49 patients (7.8%). The positive and negative predictive values were 78 and 88%, respectively. Sensitivity was 73% and specificity 91%. In patients with a true-positive CT (n = 24), reintervention followed after a median interval of 0 days (IQR 1), whereas this was 1 day (IQR 2) in the false-negative group (n = 11) (p < 0.05). This was associated with a significantly increased mortality rate (1/24 = 4.2% vs 5/11 = 45.5%) (p < 0.005), an increased length of hospital stay [median 28 days (IQR 26) vs 54 days (IQR 20) (p < 0.05)].
conclusionsDelayed reintervention after false-negative CT scanning is associated with a high mortality rate and a significant increase in length of hospital stay.
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