Evidence map›Paper›PMID 28929294›Full record

ReviewCurrent infectious disease reports2017

Neurologic Complications of Infective Endocarditis: Recent Findings.

Marie Cantier, Mikael Mazighi, Isabelle Klein, J P Desilles, Michel Wolff, J F Timsit, Romain Sonneville

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current infectious disease reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Perioperative Complications in Infective Endocarditis.Journal of clinical medicine · 2023
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Neurological Complications of Infective Endocarditis.Current neurology and neuroscience reports · 2019
    Review
  9. Imaging of cerebrovascular complications of infection.Quantitative imaging in medicine and surgery · 2018
    Review
  10. Intracranial complications of acute bacterial endocarditis.Surgical neurology international · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Marie CantierDepartment of Intensive Care Medicine and Infectious Diseases, Bichat-Claude Bernard University Hospital, Assistance Publique - Hôpitaux de Paris, 46 rue Henri Huchard, 75018, Paris, France. marie.cantier@aphp.fr.
Mikael MazighiINSERM U1148, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
Isabelle KleinImaging Department, Clinique Alleray Labrouste, Paris, France.
J P DesillesINSERM U1148, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
Michel WolffDepartment of Intensive Care Medicine and Infectious Diseases, Bichat-Claude Bernard University Hospital, Assistance Publique - Hôpitaux de Paris, 46 rue Henri Huchard, 75018, Paris, France.
J F TimsitDepartment of Intensive Care Medicine and Infectious Diseases, Bichat-Claude Bernard University Hospital, Assistance Publique - Hôpitaux de Paris, 46 rue Henri Huchard, 75018, Paris, France.
Romain SonnevilleDepartment of Intensive Care Medicine and Infectious Diseases, Bichat-Claude Bernard University Hospital, Assistance Publique - Hôpitaux de Paris, 46 rue Henri Huchard, 75018, Paris, France. romain.sonneville@aphp.fr.
Assistance Publique – Hôpitaux de Paris · FRUniversité Paris Cité · FRClinique Ambroise Paré · FRHôpital Bichat-Claude-Bernard · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe purpose of this paper is to provide recent insights in management of neurologic complications of left-sided infective endocarditis (IE). RECENT

findingsCerebral lesions observed in IE patients are thought to involve synergistic pathophysiological mechanisms including thromboembolism, sepsis, meningitis, and small-vessel cerebral vasculitis. Brain MRI represents a major tool for the detection of asymptomatic events occurring in the majority of patients. The latter can impact therapeutic decisions and prognosis, especially when cardiac surgery is indicated. In patients presenting with neurologic complications, surgery could be safely performed earlier than previously thought. Symptomatic cerebral ischemic or hemorrhagic events occur in 20-55% of IE patients, whereas asymptomatic events are detected in 60-80% of patients undergoing systematic brain MRI. Management of such patients requires an experienced multidisciplinary team. Recent studies suggest that early cardiac surgery, when indicated, can be performed safely in patients with cerebral ischemic events. Other important issues include the appropriate use of anti-infective and anti-thrombotic agents, and endovascular treatment for mycotic aneurysms. Altered mental status at IE onset, which is associated with brain injury, is a major determinant of short-term outcome.

Indexed as

Brain hemorrhageCardiac surgeryCerebral vasculitisInfective endocarditisIschemic strokeNeuroimaging

Identifiers

PMID28929294
OpenAlexW2755660205

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.