Evidence map›Paper›PMID 28929268›Full record

ArticleEuropean journal of epidemiology2017

Mother's education and offspring asthma risk in 10 European cohort studies.

Kate Marie Lewis, Milagros Ruiz, Peter Goldblatt, Joana Morrison, Daniela Porta, Francesco Forastiere, Daniel Hryhorczuk, Oleksandr Zvinchuk, Marie-Josephe Saurel-Cubizolles, Sandrine Lioret and 17 more

Open access · hybridAbstract readComparative Study
In one paragraph

Article in European journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
  2. Western dietary pattern during pregnancy and early childhood increases risk of childhood asthma dependent on socioeconomic status.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  3. Article
  4. Article
  5. Social inequalities in childhood asthma.The World Allergy Organization journal · 2024
    Review
  6. Article
  7. Structural Racism and the Social Determinants of Health in Asthma.Advances in experimental medicine and biology · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Risk factors associated with rhinitis, allergic conjunctivitis and eczema among schoolchildren in Uganda.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 14 institutions in 10 countries.

Kate Marie LewisResearch Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London, WC1E 6BT, UK.
Milagros RuizResearch Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London, WC1E 6BT, UK.
Peter GoldblattResearch Department of Epidemiology and Public Health, UCL Institute of Health Equity, University College London, London, UK.
Joana MorrisonResearch Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London, WC1E 6BT, UK.
Daniela PortaDepartment of Epidemiology, Lazio Regional Health System, Rome, Italy.
Francesco ForastiereDepartment of Epidemiology, Lazio Regional Health System, Rome, Italy.
Daniel HryhorczukCenter for Global Health, University of Illinois College of Medicine, Chicago, IL, USA.
Oleksandr ZvinchukInstitute of Pediatrics, Obstetrics, and Gynecology, National Academy of Medical Sciences of Ukraine, Kiev, Ukraine.
Marie-Josephe Saurel-CubizollesInstitut National de la Santé et de la Recherche Médicale (INSERM), UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (Epopé), Center for Epidemiology and Statistics, Sorbonne Paris Cité, DHU Risks in Pregnancy, Paris Descartes University, Paris, France.
Sandrine LioretInstitut National de la Santé et de la Recherche Médicale (INSERM), UMR 1153, Early Origin of the Child's Health and Development Team (ORCHAD), Center for Epidemiology and Statistics, Sorbonne Paris Cité, Paris Descartes University, Paris, France.
Isabella Annesi-MaesanoPierre Louis Institute of Epidemiology and Public Health (iPLESP), UMR 1136, Epidemiology of Allergic and Respiratory Diseases (EPAR), Paris, France.
Martine VrijheidISGlobal, Center for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.
Maties TorrentSpanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Barcelona, Spain.
Carmen IniguezSpanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Barcelona, Spain.
Isabel LarranagaPublic Health Department of Gipuzkoa, Gipuzkoa, Spain.
Margreet W Harskamp-van GinkelDepartment of Public Health, Amsterdam Public Health Research Institute, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Tanja G M VrijkotteDepartment of Public Health, Amsterdam Public Health Research Institute, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Jana KlanovaResearch Centre of Toxic Compounds in the Environment (RECETOX), Faculty of Science, Masaryk University, Brno, Czech Republic.
Jan SvancaraInstitute of Biostatistics and Analyses (IBA), Masaryk University, Brno, Czech Republic.
Henrique BarrossEPIUnit - Institute of Public Health, University of Porto, Porto, Portugal.
Sofia CorreiaEPIUnit - Institute of Public Health, University of Porto, Porto, Portugal.
Marjo-Riitta JarvelinDepartment of Epidemiology and Biostatistics, MRC Health Protection Agency (HPE), Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
Anja TaanilaFaculty of Medicine, Center for Life Course Health Research, University of Oulu, Oulu, Finland.
Johnny LudvigssonDivision of Pediatrics, Department of Clinical and Experimental Medicin, Linköping University, Linköping, Sweden.
Tomas FaresjoDepartment of Medicine and Health, Community Medicine/General Practice Faculty of Health Sciences, Linköping University, Linköping, Sweden.
Michael MarmotResearch Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London, WC1E 6BT, UK.
Hynek PikhartResearch Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London, WC1E 6BT, UK. h.pikhart@ucl.ac.uk.
University College London · GBCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESLinköping University · SEMasaryk University · CZUniversidade do Porto · PTUniversité Paris Cité · FRUniversity of Oulu · FIBiogipuzkoa Health Research Institute · ESGGD Amsterdam · NLInstitut Pierre Louis d‘Épidémiologie et de Santé Publique · FRNational Academy of Medical Sciences of Ukraine · UAServei de Salut de les Illes Balears · ESUniversity of Amsterdam · NLUniversity of Illinois Chicago · US

Funding

Medical Research Council 1764985
6 · The paper itself

Abstract

Highly prevalent and typically beginning in childhood, asthma is a burdensome disease, yet the risk factors for this condition are not clarified. To enhance understanding, this study assessed the cohort-specific and pooled risk of maternal education on asthma in children aged 3-8 across 10 European countries. Data on 47,099 children were obtained from prospective birth cohort studies across 10 European countries. We calculated cohort-specific prevalence difference in asthma outcomes using the relative index of inequality (RII) and slope index of inequality (SII). Results from all countries were pooled using random-effects meta-analysis procedures to obtain mean RII and SII scores at the European level. Final models were adjusted for child sex, smoking during pregnancy, parity, mother's age and ethnicity. The higher the score the greater the magnitude of relative (RII, reference 1) and absolute (SII, reference 0) inequity. The pooled RII estimate for asthma risk across all cohorts was 1.46 (95% CI 1.26, 1.71) and the pooled SII estimate was 1.90 (95% CI 0.26, 3.54). Of the countries examined, France, the United Kingdom and the Netherlands had the highest prevalence's of childhood asthma and the largest inequity in asthma risk. Smaller inverse associations were noted for all other countries except Italy, which presented contradictory scores, but with small effect sizes. Tests for heterogeneity yielded significant results for SII scores. Overall, offspring of mothers with a low level of education had an increased relative and absolute risk of asthma compared to offspring of high-educated mothers.

Indexed as

Educational StatusMothersAsthmaChildChild, PreschoolCross-Cultural ComparisonEuropeFemaleHumansMaleMaternal AgePrevalenceRisk FactorsAsthmaChildrenCohort studiesDisease riskMaternal educationSocioeconomic position

Identifiers

PMID28929268
PMCPMC5662657
OpenAlexW2754334769

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.