Evidence map›Paper›PMID 28929173›Full record

ArticleCellular and molecular life sciences : CMLS2018

Platelet-derived growth factor receptor beta identifies mesenchymal stem cells with enhanced engraftment to tissue injury and pro-angiogenic property.

Shan Wang, Miaohua Mo, Jinmei Wang, Sobia Sadia, Bihua Shi, Xiaobing Fu, Lin Yu, Edward E Tredget, Yaojiong Wu

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 76 citations in OpenAlex.

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  6. The Interplay of Angiogenesis and Osteogenesis in Non-Stabilized Incomplete Tibial Fractures: A Temporal Study in Rats.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
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  14. Intrapulmonary arterial contraction assay reveals region-specific deregulation of vasoreactivity to lung injuries.American journal of physiology. Lung cellular and molecular physiology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Shan WangSchool of Life Sciences, Tsinghua University, Beijing, China.
Miaohua MoSchool of Life Sciences, Tsinghua University, Beijing, China.
Jinmei WangThe Shenzhen Key Laboratory of Health Sciences and Technology, Graduate School at Shenzhen, Tsinghua University, L406A, Tsinghua Campus, The University Town, Shenzhen, 518055, China.
Sobia SadiaSchool of Life Sciences, Tsinghua University, Beijing, China.
Bihua ShiTsinghua-Berkeley Shenzhen Institute (TBSI), Tsinghua University, Shenzhen, China.
Xiaobing FuWound Healing and Cell Biology Laboratory, Institute of Basic Medical Science, Chinese PLA General Hospital, Beijing, China.
Lin YuPeking University Shenzhen Hospital, Shenzhen Key Laboratory of Gynecological Diagnostic Technology Research, Shenzhen, China.
Edward E TredgetWound Healing Research Group, Department of Surgery, University of Alberta, Edmonton, AB, Canada.
Yaojiong WuThe Shenzhen Key Laboratory of Health Sciences and Technology, Graduate School at Shenzhen, Tsinghua University, L406A, Tsinghua Campus, The University Town, Shenzhen, 518055, China. wu.yaojiong@sz.tsinghua.edu.cn.
Tsinghua University · CNUniversity Town of Shenzhen · CNChinese PLA General Hospital · CNPeking University Shenzhen Hospital · CNTsinghua–Berkeley Shenzhen Institute · CNUniversity of Alberta · CA

Funding

Natural Science Foundation of China No. 31371404Natural Science Foundation of China No. 31571429Natural Science Foundation of Guangdong Province (CN) 2015A030311041Shenzhen Science and Technology Innovation Committee JCY20160301150838144
6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) are heterogeneous likely consisting of subpopulations with various therapeutic potentials. Here we attempted to acquire a subset of MSCs with enhanced effect in wound healing. We found that human placental MSCs expressing platelet-derived growth factor (PDGF) receptor (PDGFR)-β exhibited greater proliferation rates and generated more colony-forming unit-fibroblast (CFU-F), compared to PDGFR-β

Indexed as

Mesenchymal Stem Cell TransplantationWound HealingAnimalsCells, CulturedCell SeparationFlow CytometryHumansMesenchymal Stem CellsMiceMice, Inbred BALB CMice, NudeNeovascularization, PhysiologicProto-Oncogene Proteins c-sisRegenerationProto-Oncogene Proteins c-sisAngiogenesisMesenchymal stem cellsPDGFR-β (CD140b)SubpopulationWound healing

Identifiers

PMID28929173
PMCPMC11105282
OpenAlexW2754082660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.