Evidence map›Paper›PMID 28929132›Full record

ArticleScience advances2017

Interplay between protein glycosylation pathways in Alzheimer's disease.

Moran Frenkel-Pinter, Merav Daniel Shmueli, Chen Raz, Michaela Yanku, Shai Zilberzwige, Ehud Gazit, Daniel Segal

Abstract read
In one paragraph

Article in Science advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. SerumJournal of proteome research · 2025
    Article
  9. Article
  10. Review
  11. Implications of Mucin-TypeMolecules (Basel, Switzerland) · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Pathways to Alzheimer's Disease: The Intersecting Roles of Clusterin and Apolipoprotein E in Amyloid-β Regulation and Neuronal Health.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Review
  18. Article
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Moran Frenkel-PinterDepartment of Molecular Microbiology and Biotechnology, Interdisciplinary Sagol School of Neurosciences, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Merav Daniel ShmueliDepartment of Molecular Microbiology and Biotechnology, Interdisciplinary Sagol School of Neurosciences, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Chen RazDepartment of Molecular Microbiology and Biotechnology, Interdisciplinary Sagol School of Neurosciences, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Michaela YankuDepartment of Molecular Microbiology and Biotechnology, Interdisciplinary Sagol School of Neurosciences, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Shai ZilberzwigeDepartment of Molecular Microbiology and Biotechnology, Interdisciplinary Sagol School of Neurosciences, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Ehud GazitDepartment of Molecular Microbiology and Biotechnology, Interdisciplinary Sagol School of Neurosciences, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.ORCID 0000-0001-5764-1720
Daniel SegalDepartment of Molecular Microbiology and Biotechnology, Interdisciplinary Sagol School of Neurosciences, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.ORCID 0000-0002-6777-505X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deviations from the normal nucleoplasmic protein O-GlcNAcylation, as well as from normal protein sialylation and N-glycosylation in the secretory pathway, have been reported in Alzheimer's disease (AD). However, the interplay between the cytoplasmic protein

Indexed as

Protein Processing, Post-TranslationalSignal TransductionAgedAged, 80 and overAlzheimer DiseaseBiomarkersBrainCase-Control StudiesFemaleGlycosylationHumansMaleMiddle AgedProteomeProteomicsBiomarkersProteome

Identifiers

PMID28929132
PMCPMC5600531

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.