Evidence map›Paper›PMID 28928996›Full record

ArticleCase reports in hematology2017

Immune-Mediated Autonomic Neuropathies following Allogeneic Stem Cell Transplantation in Acute Myeloid Leukemia.

Abhishek Mangaonkar, Hassan Al Khateeb, Narjust Duma, Erik K St Louis, Andrew McKeon, Mrinal Patnaik, William Hogan, Mark Litzow, Taxiarchis Kourelis

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in hematology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Abhishek MangaonkarDivision of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0003-2458-9887
Hassan Al KhateebDivision of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Narjust DumaDivision of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Erik K St LouisDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Andrew McKeonDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Mrinal PatnaikDivision of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
William HoganDivision of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Mark LitzowDivision of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Taxiarchis KourelisDivision of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsAutonomic dysfunction (AD) after allogeneic stem cell transplant (SCT) is a rare occurrence and likely immune-mediated in etiology. There is limited literature on this topic and hence, we wish to briefly describe management of two cases at our institution and their outcomes.

methodsWe retrospectively identified two patients with immune-mediated AD after SCT from our database. Immune-mediated AD was defined as AD secondary to an immune-mediated etiology without an alternative cause and responding to immunosuppression.

resultsThe first case is of a 32-year-old man with acute myeloid leukemia (AML) who underwent double umbilical cord allogeneic SCT. The second patient was a 51-year-old woman with secondary AML who underwent matched-related donor allogeneic SCT. Both underwent an extensive work-up for an underlying etiology prior to treatment with intravenous immunoglobulin (IVIG).

conclusionsAD after SCT is a rare yet significant clinical entity. A work-up of underlying etiology should be performed. IVIG is a treatment option for these patients.

Identifiers

PMID28928996
PMCPMC5591963
OpenAlexW2745350306

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