ArticleJournal of Cancer2017
Anti-Melanoma Activities of Haspin Inhibitor CHR-6494 Deployed as a Single Agent or in a Synergistic Combination with MEK Inhibitor.
Article in Journal of Cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Haspin balances the ratio of asymmetric cell division through Wnt5a and regulates cell fate decisions in mouse embryonic stem cells.Cell death discovery · 2023Article
- Knockdown of GSG2 inhibits the development and progression of non-small cell lung cancerCell cycle (Georgetown, Tex.) · 2023Article
- Phosphorylation of H3-Thr3 by Haspin Is Required for Primary Cilia Regulation.International journal of molecular sciences · 2021Article
- Evaluation of the antiproliferative effects of the HASPIN inhibitor CHR-6494 in breast cancer cell lines.PloS one · 2021Article
- Design of new disubstituted imidazo[1,2-Journal of enzyme inhibition and medicinal chemistry · 2020Article
- Knockdown of GSG2 inhibits prostate cancer progression in vitro and in vivo.International journal of oncology · 2020Article
- GSG2 (Haspin) promotes development and progression of bladder cancer through targeting KIF15 (Kinase-12).Aging · 2020Article
- Haspin inhibition delays cell cycle progression through interphase in cancer cells.Journal of cellular physiology · 2020Article
- A Peak of H3T3 Phosphorylation Occurs in Synchrony with Mitosis in Sea Urchin Early Embryos.Cells · 2020Article
- Bioinformatic Analysis Reveals GSG2 as a Potential Target for Breast Cancer Therapy.Open life sciences · 2019Article
- 3H-pyrazolo[4,3-f]quinoline haspin kinase inhibitors and anticancer properties.Bioorganic chemistry · 2018Article
- Arctigenin Inhibits Liver Cancer Tumorigenesis by Inhibiting Gankyrin Expression via C/EBPα and PPARα.Frontiers in pharmacology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 2 countries.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.