ArticleJournal of Cancer2017
Mechanisms of Breast Cancer in Shift Workers: DNA Methylation in Five Core Circadian Genes in Nurses Working Night Shifts.
Article in Journal of Cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 35 citations in OpenAlex.
- Therapeutic Potential of Melatonin in Gastrointestinal Cancers: Molecular Mechanisms, Preclinical Evidence and Clinical Implications.Journal of pineal research · 2026Review
- Night shift work and breast cancer: from etiopathology to precision risk analysis.NPJ breast cancer · 2025Review
- Road traffic noise and breast cancer: DNA methylation in four core circadian genes.Clinical epigenetics · 2024Article
- Digital Screen Time and the Risk of Female Breast Cancer: A Retrospective Matched Case-Control Study.Journal of biomedical physics & engineering · 2024Article
- Early-to-mid pregnancy sleep and circadian markers in relation to birth outcomes: An epigenetics pilot study.Chronobiology international · 2023Article
- Construction of Lentiviral Vector for miR-217 Overexpression and Knockdown and Its Effect on CML.Molecular biotechnology · 2023Article
- The association between night shift work and breast cancer risk in the Finnish twins cohort.European journal of epidemiology · 2023Article
- Article
- Occupational risk factors and breast cancer in Beijing, China: a hospital-based case-control study.BMJ open · 2022Article
- Assessment of risks for breast cancer in a flight attendant exposed to night shift work and cosmic ionizing radiation: a case report.Annals of occupational and environmental medicine · 2022Article
- Women's health and night shift work: Potential targets for future strategies in breast cancer (Review).Biomedical reports · 2021Review
- Cross-species physiological interactions of endocrine disrupting chemicals with the circadian clock.General and comparative endocrinology · 2021Review
- A Comparative Study of HOTAIR Expression in Breast Cancer Patient Tissues and Cell Lines.Cell journal · 2020Article
- The Cancer Clock Is (Not) Ticking: Links between Circadian Rhythms and Cancer.Clocks & sleep · 2019Review
- Article
- ARNTL hypermethylation promotes tumorigenesis and inhibits cisplatin sensitivity by activating CDK5 transcription in nasopharyngeal carcinoma.Journal of experimental & clinical cancer research : CR · 2019Article
- Expression Analysis of MALAT1, GAS5, SRA, and NEAT1 lncRNAs in Breast Cancer Tissues from Young Women and Women over 45 Years of Age.Molecular therapy. Nucleic acids · 2018Article
- Panomics for Precision Medicine.Trends in molecular medicine · 2018Review
- Impact of shift work on the diurnal cortisol rhythm: a one-year longitudinal study in junior physicians.Journal of occupational medicine and toxicology (London, England) · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Shift work has been suggested to be associated with breast cancer risk, and circadian disruption in shift workers is hypothesized as one of the mechanisms of increased cancer risk. There is, however, insufficient molecular evidence supporting this hypothesis. Using the quantitative methodology of pyrosequencing, epigenetic changes in 5-methyl cytosine (5mC) in five circadian genes
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.