Evidence map›Paper›PMID 28928766›Full record

ArticleFrontiers in genetics2017

Genetics of Tinnitus: Time to Biobank Phantom Sounds.

Christopher R Cederroth, Anna K Kähler, Patrick F Sullivan, Jose A Lopez-Escamez

Abstract read
In one paragraph

Article in Frontiers in genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Modifiable risk factors for tinnitus: A Mendelian randomization study.The Journal of international medical research · 2026
    Pooled it
  2. Article
  3. Goal Attainment Scale in tinnitus (GAS-T): treatment goal priorities by chronic tinnitus patients in a real-world setting.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  4. Limited Link of Common Blood Parameters with Tinnitus.Journal of clinical medicine · 2023
    Article
  5. Tinnitus and Influencing Comorbidities.Laryngo- rhino- otologie · 2023
    Review
  6. Article
  7. Article
  8. Review
  9. Association between Hyperacusis and Tinnitus.Journal of clinical medicine · 2020
    Article
  10. Article
  11. Article
  12. Why Is There No Cure for Tinnitus?Frontiers in neuroscience · 2019
    Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christopher R CederrothExperimental Audiology, Department of Physiology and Pharmacology, Karolinska InstitutetStockholm, Sweden.
Anna K KählerDepartment of Molecular Epidemiology and Biostatistics, Karolinska InstitutetStockholm, Sweden.
Patrick F SullivanDepartment of Molecular Epidemiology and Biostatistics, Karolinska InstitutetStockholm, Sweden.
Jose A Lopez-EscamezOtology & Neurotology Group, Department of Genomic Medicine, Pfizer-Universidad de Granada-Junta de Andalucía Centre for Genomics and Oncology Research (GENyO)Granada, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tinnitus is a common phantom sensation resulting most often from sensory deprivation, and for which little knowledge on the molecular mechanisms exists. While the existing evidence for a genetic influence on the condition has been until now sparse and underpowered, recent data suggest that specific forms of tinnitus have a strong genetic component revealing that not all tinnitus percepts are alike, at least in how they are genetically driven. These new findings pave the way for a better understanding on how phantom sensations are molecularly driven and call for international biobanking efforts.

Indexed as

geneticsGWAS (genome-wide association study)heritabilityneuropsychiatrysubtypetinnituswhole exome sequencing

Identifiers

PMID28928766
PMCPMC5591447

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.