ArticleScientific reports2017
Nanoscale compositional mapping of cells, tissues, and polymers with ringing mode of atomic force microscopy.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Unveiling Van Der Waals Forces and Associated Hamaker Constants Across the Nanomaterial Landscape With Advanced Atomic Force Microscopy.Small methods · 2026Review
- Nanoscale Imaging of Biological Tissues: Techniques, Challenges and Emerging Frontiers.Nanomaterials (Basel, Switzerland) · 2025Review
- Advances in nanomechanical property mapping by atomic force microscopy.Nanoscale advances · 2025Review
- High-Speed Quantitative Nanomechanical Mapping by Photothermal Off-Resonance Atomic Force Microscopy.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Detection of Human Bladder Epithelial Cancerous Cells with Atomic Force Microscopy and Machine Learning.Cells · 2024Article
- Mechanical spectroscopy of materials using atomic force microscopy (AFM-MS).Materials today (Kidlington, England) · 2024Article
- Applying the Atomic Force Microscopy Technique in Medical Sciences-A Narrative Review.Biomedicines · 2024Review
- On machine learning analysis of atomic force microscopy images for image classification, sample surface recognition.Physical chemistry chemical physics : PCCP · 2024Review
- Cell Surface Parameters for Accessing Neutrophil Activation Level with Atomic Force Microscopy.Cells · 2024Article
- Enhanced feedback performance in off-resonance AFM modes through pulse train sampling.Beilstein journal of nanotechnology · 2024Article
- Review
- The dynamics of the endothelial glycocalyx: a rare snapshot by electron microscopy.Angiogenesis · 2023Article
- Article
- Review
- Acceleration of imaging in atomic force microscopy working in sub-resonance tapping mode.The Review of scientific instruments · 2022Article
- Few-cycle Regime Atomic Force Microscopy.Scientific reports · 2019Article
- Mechanics of Brain Tissues Studied by Atomic Force Microscopy: A Perspective.Frontiers in neuroscience · 2019Review
- Noninvasive diagnostic imaging using machine-learning analysis of nanoresolution images of cell surfaces: Detection of bladder cancer.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- AFM Monitoring the Influence of Selected Cryoprotectants on Regeneration of Cryopreserved Cells Mechanical Properties.Frontiers in physiology · 2018Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently developed sub-resonance tapping modes (such as Digital Pulse, Peak Force Tapping, HybriD, etc.) of atomic force microscopy (AFM) allow imaging of compositional contrast of (bio)materials and biological cells down to the nanoscale. Here we report on a powerful extension of those modes, "ringing" mode, which more than doubles the number of non-trivial physical channels that can be collected with a regular sub-resonance tapping. It can simultaneously record five new additional compositional parameters related to adhesive and viscoelastic properties of the sample surface: the restored (averaged) adhesion, adhesion height, pull-off neck height, detachment distance, and detachment energy losses. Ringing mode can be up to 20 times faster and showing fewer artifacts compared to the existing sub-resonance tapping modes. Ringing mode is based on an analysis of ringing signal of the AFM cantilever after detaching the AFM probe from the sample surface (this signal is currently treated as noise, and typically filtered out in the existing modes). We demonstrate that this new mode allows recording robust and unique information on fixed human epithelial cells, corneocyte skin flakes, and polymers used for bioimplants.
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