ArticleScientific reports2017
Genome characterization of two bile-isolated Vibrio fluvialis strains: an insight into pathogenicity and bile salt adaption.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Vibrio fluvialis Bacteremia in an Immunocompetent Patient with Acute Cholangitis.Internal medicine (Tokyo, Japan) · 2024Article
- From Natural Microbe Screening to Sustained Chitinase Activity in Exogenous Hosts.ACS synthetic biology · 2024Article
- Role of Bacteriophages in the Evolution of Pathogenic Vibrios and Lessons for Phage Therapy.Advances in experimental medicine and biology · 2023Article
- Accurate Identification of Diverse N-acyl Homoserine Lactones in Marine Vibrio fluvialis by UHPLC-MS/MS.Current microbiology · 2022Article
- Population genomics of the food-borne pathogenMicrobial genomics · 2022Article
- Population Analysis of Vibrio cholerae in Aquatic Reservoirs Reveals a Novel Sister Species (Applied and environmental microbiology · 2021Article
- Cultivation and Genomic Characterization of the Bile Bacterial Species From Cholecystitis Patients.Frontiers in microbiology · 2021Article
- The Great ESKAPE: Exploring the Crossroads of Bile and Antibiotic Resistance in Bacterial Pathogens.Infection and immunity · 2020Review
- Gallstone Disease and Microbiome.Microorganisms · 2020Review
- Co-Existence ofInfection and drug resistance · 2020Article
- Whole Genome Sequencing of Extended-Spectrum Beta-Lactamase (ESBL)-ProducingFrontiers in microbiology · 2019Article
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13 authors.
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Abstract
Vibrio fluvialis is recognized as an emerging pathogen. However, not much is known about the mechanism of its pathogenesis, and its adaptation to a special niche such as the gall bladder. Here we describe two V. fluvialis strains that cause acute cholecystitis. It is noteworthy that both strains were susceptible to all antibiotics tested, which is in contrast to previous studies, suggesting substantial genetic diversity among V. fluvialis isolates. In agreement with their survival and growth in the gall bladder, the genomes of strains 12605 and 3663 contain a considerable number of genes that confer resistance to bile, including toxR, omp U, tolC, cmeABC, rlpB, yrbK, rpoS, damX and gltK. Furthermore, integrative and conjugative elements (ICEs), virulence factors and prophage regions were also detected in strains 12605 and 3663, reflecting their flexibility in recombination during the evolution of pathogenicity. Comparative analysis of nine available genomes of V. fluvialis revealed a core genome consisting of 3,147 genes. Our results highlight the association of V. fluvialis with a rare disease profile and shed light on the evolution of pathogenesis and niche adaptation of V. fluvialis.
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