Evidence map›Paper›PMID 28928410›Full record

ArticleScientific reports2017

Ang-(1-7) is an endogenous β-arrestin-biased agonist of the AT

Larissa B Teixeira, Lucas T Parreiras-E-Silva, Thiago Bruder-Nascimento, Diego A Duarte, Sarah C Simões, Rafael M Costa, Deisy Y Rodríguez, Pedro A B Ferreira, Carlos A A Silva, Emiliana P Abrao and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 105 citations in OpenAlex.

  1. Article
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  6. Review
  7. Alternative Renin-Angiotensin System.Hypertension (Dallas, Tex. : 1979) · 2024
    Review
  8. Application of Photodynamic Therapy in Cardiology.International journal of molecular sciences · 2024
    Review
  9. Insights Into the Role of Angiotensin-II ATHypertension (Dallas, Tex. : 1979) · 2024
    Review
  10. Review
  11. Article
  12. Article
  13. The Renin Angiotensin System as a Therapeutic Target in Traumatic Brain Injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
  14. The ATMolecules (Basel, Switzerland) · 2023
    Review
  15. Review
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Larissa B TeixeiraDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto, SP, 14049-900, Brazil.
Lucas T Parreiras-E-SilvaDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto, SP, 14049-900, Brazil.
Thiago Bruder-NascimentoDepartment of Pharmacology, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto, SP, 14049-900, Brazil.
Diego A DuarteDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto, SP, 14049-900, Brazil.
Sarah C SimõesDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto, SP, 14049-900, Brazil.
Rafael M CostaDepartment of Pharmacology, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto, SP, 14049-900, Brazil.
Deisy Y RodríguezDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto, SP, 14049-900, Brazil.
Pedro A B FerreiraDepartment of Pharmacology, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto, SP, 14049-900, Brazil.
Carlos A A SilvaDepartment of Pharmacology, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto, SP, 14049-900, Brazil.
Emiliana P AbraoDepartment of Pharmacology, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto, SP, 14049-900, Brazil.
Eduardo B OliveiraDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto, SP, 14049-900, Brazil.
Michel BouvierDepartment of Biochemistry and Molecular Medicine and Institute for Research in Immunology and Cancer, University of Montréal, Montréal, QC, H3C-3J7, Canada.ORCID 0000-0003-1128-0100
Rita C TostesDepartment of Pharmacology, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto, SP, 14049-900, Brazil.
Claudio M Costa-NetoDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto, SP, 14049-900, Brazil. claudio@fmrp.usp.br.
Universidade de São Paulo · BRInstitute for Research in Immunology and Cancer · CAUniversidade de Ribeirão Preto · BR

Funding

CIHR
6 · The paper itself

Abstract

The renin-angiotensin system (RAS) plays a key role in the control of vasoconstriction as well as sodium and fluid retention mediated mainly by angiotensin (Ang) II acting at the AT

Indexed as

Angiotensin IAnimalsbeta-ArrestinsCardiomegalyCardiotonic AgentsDiastoleHeartHEK293 CellsHumansMaleMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Peptide FragmentsPhosphorylationRatsRats, Inbred WFAngiotensin Iangiotensin I (1-7)beta-ArrestinsCardiotonic AgentsMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Peptide FragmentsReceptor, Angiotensin, Type 1

Identifiers

PMID28928410
PMCPMC5605686
OpenAlexW2754957776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.