ArticleNature communications2017
Analysis of the pressure requirements for silk spinning reveals a pultrusion dominated process.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed.
- Targeting the circadian negative regulatorMaterials today. Bio · 2026Article
- The stage-wise macromolecular assembly and structure evolution of silk along the silk gland.Nature communications · 2026Article
- Bioinspired micro-structured fibers for biomedical applications.Bioactive materials · 2025Review
- Article
- High-yield spidroin mimics for bioinspired fibers via computational design.Frontiers in bioengineering and biotechnology · 2025Article
- Calcium ion-triggered liquid-liquid phase separation of silk fibroin and spinning through acidification and shear stress.Nature communications · 2024Article
- Progress in Multiscale Modeling of Silk Materials.Biomacromolecules · 2024Review
- Strategies for Making High-Performance Artificial Spider Silk Fibers.Advanced functional materials · 2024Review
- Origin, structure, and composition of the spider major ampullate silk fiber revealed by genomics, proteomics, and single-cell and spatial transcriptomics.Science advances · 2024Article
- Redefining Surgical Materials: Applications of Silk Fibroin in Osteofixation and Fracture Repair.Biomimetics (Basel, Switzerland) · 2024Review
- The ratio of fibroin to sericin in the middle silk gland of Bombyx mori and its correlation with the extensional behavior of the silk dope.Protein science : a publication of the Protein Society · 2024Article
- Replicating shear-mediated self-assembly of spider silk through microfluidics.Nature communications · 2024Article
- The role of flow in the self-assembly of dragline spider silk proteins.Biophysical journal · 2023Article
- Continuous Wet Spinning of Regenerated Silk Fibers from Spinning Dopes Containing 4% Fibroin Protein.International journal of molecular sciences · 2023Article
- Flow-Induced Protein Chain Deformation, Segmental Orientation, and Phase Separation in Native Silk Feedstock.Biomacromolecules · 2023Article
- Kinetic Analysis Reveals the Role of Secondary Nucleation in Regenerated Silk Fibroin Self-Assembly.Biomacromolecules · 2023Article
- Dynamic Changes and Characterization of the Metal Ions in the Silk Glands and Silk Fibers of Silkworm.International journal of molecular sciences · 2023Article
- A brief review on the mechanisms and approaches of silk spinning-inspired biofabrication.Frontiers in bioengineering and biotechnology · 2023Review
- Molecular mechanisms of the high performance of spider silks revealed through multi-omics analysis.Biophysics and physicobiology · 2023Article
- Engineered Spider Silk Proteins for Biomimetic Spinning of Fibers with Toughness Equal to Dragline Silks.Advanced functional materials · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Silks are remarkable materials with desirable mechanical properties, yet the fine details of natural production remain elusive and subsequently inaccessible to biomimetic strategies. Improved knowledge of the natural processes could therefore unlock development of a host of bio inspired fibre spinning systems. Here, we use the Chinese silkworm Bombyx mori to review the pressure requirements for natural spinning and discuss the limits of a biological extrusion domain. This provides a target for finite element analysis of the flow of silk proteins, with the aim of bringing the simulated and natural domains into closer alignment. Supported by two parallel routes of experimental validation, our results indicate that natural spinning is achieved, not by extruding the feedstock, but by the pulling of nascent silk fibres. This helps unravel the oft-debated question of whether silk is pushed or pulled from the animal, and provides impetus to the development of pultrusion-based biomimetic spinning devices.The natural production of silks remains elusive and subsequently inaccessible to biomimetic strategies. Here the authors show that silks cannot be spun by pushing alone, and that natural spinning is dominated by pultrusion, which provides design guidelines for future biomimetic spinning systems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.