Evidence map›Paper›PMID 28928218›Full record

ArticleThe Journal of biological chemistry2017

The serine protease homolog CLIPA14 modulates the intensity of the immune response in the mosquito

Johnny Nakhleh, George K Christophides, Mike A Osta

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 47 citations in OpenAlex.

  1. Partial reconstitution of the prophenoloxidase activation system inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. The expanded immunoregulatory protease network in mosquitoes is governed by gene coexpression.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Review
  6. Article
  7. Late sporogonic stages ofbioRxiv : the preprint server for biology · 2024
    Article
  8. Article
  9. Late sporogonic stages ofFrontiers in cellular and infection microbiology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Frontiers in immunology · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Trained Immunity inFrontiers in microbiology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Johnny NakhlehFrom the Department of Biology, American University of Beirut, Beirut 1107 2020, Lebanon and.
George K ChristophidesDepartment of Life Sciences, Imperial College London, London SW7 2AZ, United Kingdom.
Mike A OstaFrom the Department of Biology, American University of Beirut, Beirut 1107 2020, Lebanon and mo07@aub.edu.lb.
American University of Beirut · LBImperial College London · GB

Funding

Wellcome TrustWellcome Trust 093587/Z/10/ZWellcome Trust 107983/Z/15/Z
6 · The paper itself

Abstract

Clip domain serine protease homologs (SPHs) are positive and negative regulators of

Indexed as

Immunity, InnateAnimalsAnimals, Genetically ModifiedAnophelesEnzyme ActivationEscherichia coliFemaleGene Knockdown TechniquesHemolymphInsect ProteinsIsoenzymesMelaninsMonophenol MonooxygenasePlasmodium bergheiProteolysisRNA InterferenceInsect ProteinsIsoenzymesMelaninsMonophenol MonooxygenaseSerine EndopeptidasesTEP1 protein, Anopheles gambiaetrypsin-like serine proteaseclip domain serine proteasehost defensehost-pathogen interactionimmunologymalariamelanizationmosquito immunityplasmodium

Identifiers

PMID28928218
PMCPMC5672044
OpenAlexW2756087808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.