Evidence map›Paper›PMID 28928212›Full record

ArticlemBio2017

Population and Whole Genome Sequence Based Characterization of Invasive Group A Streptococci Recovered in the United States during 2015.

Sopio Chochua, Ben J Metcalf, Zhongya Li, Joy Rivers, Saundra Mathis, Delois Jackson, Robert E Gertz, Velusamy Srinivasan, Ruth Lynfield, Chris Van Beneden and 2 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 1 pooled it
16.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 1 synthesis or guideline pooled it, 133 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Epidemiology of Pediatric Invasive Group A Streptococcal Infections in 10 US States, 2004-2023.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  4. Sudden re-emergence ofNew microbes and new infections · 2026
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  5. Identification ofAntimicrobial agents and chemotherapy · 2026
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  8. The rise and spread of invasiveMicrobial genomics · 2026
    Article
  9. Article
  10. Increase of macrolide resistance amongAntimicrobial agents and chemotherapy · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. The burden of group AiScience · 2025
    Review
  15. Article
  16. Clinical microbiology reviews · 2024
    Review
  17. Molecular characterization ofMicrobial genomics · 2024
    Article
  18. Local Genomic Surveillance of InvasiveInternational journal of molecular sciences · 2024
    Article
  19. Article
  20. Outbreak ofMicrobiology spectrum · 2024
    Article

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Sopio ChochuaNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Ben J MetcalfNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Zhongya LiNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Joy RiversNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Saundra MathisNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Delois JacksonNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Robert E GertzNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Velusamy SrinivasanNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Ruth LynfieldMinnesota Department of Health, St. Paul, Minnesota, USA.
Chris Van BenedenNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Lesley McGeeNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Bernard BeallNational Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA bbeall@cdc.gov.
Centers for Disease Control and Prevention · USNational Center for Immunization and Respiratory Diseases · USMinnesota Department of Health · US

Funding

Wellcome Trust
6 · The paper itself

Abstract

Group A streptococci (GAS) are genetically diverse. Determination of strain features can reveal associations with disease and resistance and assist in vaccine formulation. We employed whole-genome sequence (WGS)-based characterization of 1,454 invasive GAS isolates recovered in 2015 by Active Bacterial Core Surveillance and performed conventional antimicrobial susceptibility testing. Predictions were made for genotype, GAS carbohydrate, antimicrobial resistance, surface proteins (M family, fibronectin binding, T, R28), secreted virulence proteins (Sda1, Sic, exotoxins), hyaluronate capsule, and an upregulated

Indexed as

Genome, BacterialHigh-Throughput Nucleotide SequencingAnti-Bacterial AgentsGenetic VariationGenotypeHumansPhylogenyStreptococcal InfectionsStreptococcal VaccinesStreptococcus pyogenesUnited StatesVirulenceVirulence FactorsAnti-Bacterial AgentsStreptococcal VaccinesVirulence Factorsinvasive group A streptococcistreptococcal disease seasonalitystreptococcal geneticsstreptococcal resistancestreptococcal virulence featuresStreptococcus pyogenes vaccines

Identifiers

PMID28928212
PMCPMC5605940
OpenAlexW2754430056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.