Evidence map›Paper›PMID 28928071›Full record

SynthesisNeuroscience and biobehavioral reviews2017

A behavioral and cognitive neuroscience perspective on impulsivity, suicide, and non-suicidal self-injury: Meta-analysis and recommendations for future research.

Richard T Liu, Zoë M Trout, Evelyn M Hernandez, Shayna M Cheek, Nimesha Gerlus

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Neuroscience and biobehavioral reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  20. Hair cortisol concentrations as a putative biomarker for suicidal behavior.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Richard T LiuDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, United States. Electronic address: rtliupsych@gmail.com.
Zoë M TroutDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, United States.
Evelyn M HernandezDepartment of Psychiatry and Human Behavior, Alpert Medical School of Brown University, United States.
Shayna M CheekDepartment of Psychology and Neuroscience, Duke University, United States.
Nimesha GerlusDepartment of Cognitive, Linguistic, and Psychological Sciences, Brown University, United States.

Funding

Life Stressors, Impulsivity, and Adolescent Suicidal BehaviorR01MH101138 · NIMH · EMMA PENDLETON BRADLEY HOSPITAL · PI LIU, RICHARD T · 2014 to 2018
$2.0M
Modulating impulsivity in suicidal adolescents with tDCS: A proof concept studyR21MH112055 · NIMH · EMMA PENDLETON BRADLEY HOSPITAL · PI LIU, RICHARD T · 2017 to 2018
$394k
NIMH NIH HHS R01 MH101138NIMH NIH HHS R21 MH112055
6 · The paper itself

Abstract

We conducted a meta-analysis of neurobehavioral and neurocognitive indices of impulsivity in relation to suicidal thoughts and behaviors, as well as non-suicidal self-injury (NSSI). In our systematic review, 34 studies were identified and submitted to a random-effects meta-analysis. A small pooled effect size was observed for the association between behavioral impulsivity and NSSI (OR=1.34, p<0.05). A small-to-medium pooled effect size (OR=2.23, p<0.001) was found for the association between behavioral impulsivity and suicide attempts, and a medium-to-large pooled effect size was observed for this outcome in relation to cognitive impulsivity (OR=3.14, p<0.01). Length of time between suicide attempt and impulsivity assessment moderated the strength of the relation between impulsivity and attempts, with a large pooled effect size (OR=5.54, p<0.001) evident when the suicide attempt occurred within a month of behavioral impulsivity assessment. Studies of clinically significant NSSI temporally proximal to impulsivity assessment are needed. Longitudinal research is required to clarify the prognostic value of behavioral and cognitive impulsivity for short-term risk for self-harm.

Indexed as

Cognitive NeuroscienceHumansImpulsive BehaviorSelf-Injurious BehaviorSuicideImpulsivityNon-suicidal self-injurySuicidal ideationSuicideSuicide attempts

Identifiers

PMID28928071
PMCPMC5730462

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.