Evidence map›Paper›PMID 28927897›Full record

ReviewClinical nutrition (Edinburgh, Scotland)2018

Does nutrition play a role in the prevention and management of sarcopenia?

S M Robinson, J Y Reginster, R Rizzoli, S C Shaw, J A Kanis, I Bautmans, H Bischoff-Ferrari, O Bruyère, M Cesari, B Dawson-Hughes and 10 more

2 registry-linked trialsOpen access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinical nutrition (Edinburgh, Scotland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 229 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
229citing papers in PubMed, 15 pooled it
18.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06933823 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Dietary Modification Intervention Involving Family Support (FamNUTRI) for Managing Sarcopenic Obesity Among Community-dwelling Older Adults: a Pilot Randomized Controlled Trial

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2025 to 2026Enrolled72ConditionsSarcopenic ObesityArmsDietary modification intervention involving family support, Dietary modification intervention
NCT07737119 nacompletednot on this mapstarted 2024, after this paper: background citation

Impact of Optimised Protein Intake on Household Work Limitations and Disability in Rheumatoid Arthritis

TypeinterventionalSponsorSatguru Partap Singh HospitalsRan2024 to 2025Enrolled120ConditionsRheumatoid Arthritis (RA)ArmsProtein Optimisation through Dietary Counselling and Supplementation
3 · Its place in the literature

Who cites it

229 citing papers in PubMed, 15 syntheses or guidelines pooled it, 470 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Understanding the gut microbiota and sarcopenia: a systematic review.Journal of cachexia, sarcopenia and muscle · 2021
    Pooled it
  14. Pooled it
  15. Pooled it
  16. Trial
  17. Trial
  18. International journal of medical sciences · 2026
    Trial
  19. Trial
  20. Trial

169 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 14 institutions in 9 countries.

S M RobinsonMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
J Y ReginsterDepartment of Public Health, Epidemiology, and Health Economics, University of Liège, Quartier Hôpital, Liège, Belgium.
R RizzoliDivision of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, Geneva 14, Switzerland.
S C ShawMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK.
J A KanisInstitute for Health and Aging, Catholic University of Australia, Melbourne, Australia; University of Sheffield Medical School, Sheffield, UK.
I BautmansGerontology and Frailty in Ageing Research Department, Vrije Universiteit Brussel (VUB), Brussels, Belgium.
H Bischoff-FerrariDepartment of Geriatrics and Aging Research, University of Zurich, Zurich, Switzerland.
O BruyèreDepartment of Public Health, Epidemiology, and Health Economics, University of Liège, Quartier Hôpital, Liège, Belgium.
M CesariGérontopôle, University Hospital of Toulouse, Toulouse, France; INSERM UMR1027, University of Toulouse III Paul Sabatier, Toulouse, France.
B Dawson-HughesBone Metabolism Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA.
R A FieldingNutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, USA.
J M KaufmanDepartment of Endocrinology, Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, Ghent, Belgium.
F LandiDepartment of Geriatrics, Neurosciences and Orthopedics, Catholic University of the Sacred Heart Rome, Milano, Italy.
V MalafarinaDepartment of Nutrition, Food Science and Physiology, School of Pharmacy and Nutrition, University of Navarra, Pamplona, Spain; Department of Geriatrics, Complejo Hospitalario de Navarra, Pamplona, Spain.
Y RollandGérontopôle de Toulouse, Institut du Vieillissement, Centre Hospitalo-Universitaire de Toulouse (CHU Toulouse), UMR INSERM 1027, University of Toulouse III, Toulouse, France.
L J van LoonNUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University, Maastricht, Netherlands.
B VellasGérontopôle, CHU Toulouse, Service de Médecine Interne et Gérontologie Clinique, 170 Avenue de Casselardit, 31059 Toulouse, France.
M VisserDepartment of Health Sciences, Vrije Universiteit, Amsterdam, Netherlands; Department of Nutrition and Dietetics, Internal Medicine, VU University Medical Center, Amsterdam, Netherlands.
C CooperMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK; National Institute for Health Research Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford OX3 7LE, UK. Electronic address: cc@mrc.soton.ac.uk.
ESCEO working group
Southampton General Hospital · GBGhent University Hospital · BEVrije Universiteit Amsterdam · NLMaastricht University · NLTufts University · USUniversité Toulouse III - Paul Sabatier · FRUniversity of Liège · BEVrije Universiteit Brussel · BEAustralian Catholic University · AUComplejo Hospitalario de Navarra · ESMédipole Garonne · FRUniversità Cattolica del Sacro Cuore · ITUniversity Hospital of Geneva · CHUniversity of Zurich · CH

Funding

Medical Research Council G0400491Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Medical Research Council MC_UP_A620_1014Medical Research Council MC_UP_A620_1015Medical Research Council MC_UU_12011/1Medical Research Council MC_UU_12011/2
6 · The paper itself

Abstract

There is a growing body of evidence that links nutrition to muscle mass, strength and function in older adults, suggesting that it has an important role to play both in the prevention and management of sarcopenia. This review summarises the discussions of a working group [ESCEO working group meeting 8th September 2016] that met to review current evidence and to consider its implications for preventive and treatment strategies. The review points to the importance of 'healthier' dietary patterns that are adequate in quality in older age, to ensure sufficient intakes of protein, vitamin D, antioxidant nutrients and long-chain polyunsaturated fatty acids. In particular, there is substantial evidence to support the roles of dietary protein and physical activity as key anabolic stimuli for muscle protein synthesis. However, much of the evidence is observational and from high-income countries. Further high-quality trials, particularly from more diverse populations, are needed to enable an understanding of dose and duration effects of individual nutrients on function, to elucidate mechanistic links, and to define optimal profiles and patterns of nutrient intake for older adults.

Indexed as

SarcopeniaAdultAgedExerciseFemaleHumansMaleMiddle AgedMuscle, SkeletalMuscle StrengthNutritional Physiological PhenomenaMuscle massMuscle strengthNutritionPhysical performanceSarcopeniaSupplementation

Identifiers

PMID28927897
PMCPMC5796643
OpenAlexW2748094183

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.