ArticleParasites & vectors2017
Current status of insecticide resistance among malaria vectors in Kenya.
Article in Parasites & vectors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
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- Residual efficacy of SumiShield™ 50WG for indoor residual spraying in Ethiopia.Malaria journal · 2022Trial
- World Malaria Day 2026: Driven to End Malaria.China CDC weekly · 2026Article
- Insecticide resistance profiles of Anopheles arabiensis and relationship with Microsporidia MB infection in two rice agroecosystems in Kenya.Parasites & vectors · 2026Article
- Identifying antimalarials that disrupt malaria parasite transmission when fed to the mosquito.International journal for parasitology · 2025Article
- Plasmodium falciparum Pfs47 haplotype compatibility to Anopheles gambiae in Kisumu, a malaria-endemic region of Kenya.Scientific reports · 2025Article
- Insecticide resistance intensity inCurrent research in parasitology & vector-borne diseases · 2025Article
- Key gene modules and hub genes associated with pyrethroid and organophosphate resistance in Anopheles mosquitoes: a systems biology approach.BMC genomics · 2024Article
- Spatio-temporal characterization of phenotypic resistance in malaria vector species.BMC biology · 2024Article
- The Anopheles coluzzii range extends into Kenya: detection, insecticide resistance profiles and population genetic structure in relation to conspecific populations in West and Central Africa.Malaria journal · 2024Article
- Whole transcriptomic analysis reveals overexpression of salivary gland and cuticular proteins genes in insecticide-resistant Anopheles arabiensis from Western Kenya.BMC genomics · 2024Article
- TheResearch square · 2024Article
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- Sibling Species Composition and Susceptibility Status ofJournal of parasitology research · 2023Article
- A prospective cohort study of Plasmodium falciparum malaria in three sites of Western Kenya.Parasites & vectors · 2022Article
- Long-lasting insecticide-treated net use and malaria infections on the Kenyan coast.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2022Article
- Detection and population genetic analysis of kdr L1014F variant in eastern Ethiopian Anopheles stephensi.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2022Article
- Putative pleiotropic effects of the knockdown resistance (L1014F) allele on the life-history traits of Anopheles gambiae.Malaria journal · 2021Article
- Genetic markers associated with insecticide resistance and resting behaviour in Anopheles gambiae mosquitoes in selected sites in Kenya.Malaria journal · 2021Article
- Secondary malaria vectors in western Kenya include novel species with unexpectedly high densities and parasite infection rates.Parasites & vectors · 2021Article
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInsecticide resistance has emerged as one of the major challenges facing National Malaria Control Programmes in Africa. A well-coordinated national database on insecticide resistance (IRBase) can facilitate the development of effective strategies for managing insecticide resistance and sustaining the effectiveness of chemical-based vector control measures. The aim of this study was to assemble a database on the current status of insecticide resistance among malaria vectors in Kenya.
methodsData was obtained from published literature through PubMed, HINARI and Google Scholar searches and unpublished literature from government reports, research institutions reports and malaria control programme reports. Each data source was assigned a unique identification code and entered into Microsoft Excel 2010 datasheets. Base maps on the distribution of insecticide resistance and resistance mechanisms among malaria vectors in Kenya were generated using ArcGIS Desktop 10.1 (ESRI, Redlands, CA, USA).
resultsInsecticide resistance status among the major malaria vectors in Kenya was reported in all the four classes of insecticides including pyrethroids, carbamates, organochlorines and organophosphates. Resistance to pyrethroids has been detected in Anopheles gambiae (s.s.), An. arabiensis and An. funestus (s.s.) while resistance to carbamates was limited to An. gambiae (s.s.) and An. arabiensis. Resistance to the organochlorine was reported in An. gambiae (s.s.) and An. funestus (s.s.) while resistance to organophosphates was reported in An. gambiae (s.l.) only. The mechanisms of insecticide resistance among malaria vectors reported include the kdr mutations (L 1014S and L 1014F) and elevated activity in carboxylesterase, glutathione S-transferases (GST) and monooxygenases. The kdr mutations L 1014S and L 1014F were detected in An. gambiae (s.s.) and An. arabiensis populations. Elevated activity of monooxygenases has been detected in both An. arabiensis and An. gambiae (s.s.) populations while the elevated activity of carboxylesterase and GST has been detected only in An. arabiensis populations.
conclusionsThe geographical maps show the distribution of insecticide resistance and resistance mechanisms among malaria vectors in Kenya. The database generated will provide a guide to intervention policies and programmes in the fight against malaria.
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