Evidence map›Paper›PMID 28927372›Full record

Observational studyBMC geriatrics2017

Potentially inappropriate medication use in nursing homes: an observational study using the NORGEP-NH criteria.

Gunhild Nyborg, Mette Brekke, Jørund Straand, Svein Gjelstad, Maria Romøren

2 registry-linked trialsOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC geriatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01023763 phase2completednot on this map

Can a Structured Training Program in Intravenous Treatment of Infections in Nursing Homes Lead to a Better Patient Trajectory and Reduced Hospital Admittance?

TypeinterventionalSponsorUniversity of OsloRan2009 to 2012Enrolled330ConditionsInfections, DehydrationArmsA structured training program
NCT03736577 nacompletednot on this mapstarted 2018, after this paper: background citation

Psychotropic Drug Use in the Elderly Living in Nursing Homes - Associations With Clinical Symptoms and the Influence of a Structured Drug Review

TypeinterventionalSponsorOstfold Hospital TrustRan2018 to 2019Enrolled224ConditionsCognitive Symptom, Depression, Anxiety, Neuropsychiatric SyndromeArmsDrug reviews with NorGeP-NH
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
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  9. Comparative analysis of PIM criteria and drug labels in the elderly.European journal of clinical pharmacology · 2022
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  18. [Interventions to optimise prescribing for older people in care homes].Zeitschrift fur Gerontologie und Geriatrie · 2020
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gunhild NyborgDepartment of General Practice/Family Medicine, HELSAM, Institute of Health and Society, University of Oslo, P.o. Box 1130 Blindern, 0318, Oslo, Norway. gunhild.nyborg@medisin.uio.no.ORCID 0000-0001-8098-5169
Mette BrekkeDepartment of General Practice/Family Medicine, HELSAM, Institute of Health and Society, University of Oslo, P.o. Box 1130 Blindern, 0318, Oslo, Norway.
Jørund StraandDepartment of General Practice/Family Medicine, HELSAM, Institute of Health and Society, University of Oslo, P.o. Box 1130 Blindern, 0318, Oslo, Norway.
Svein GjelstadDepartment of General Practice/Family Medicine, HELSAM, Institute of Health and Society, University of Oslo, P.o. Box 1130 Blindern, 0318, Oslo, Norway.
Maria RomørenDepartment of General Practice/Family Medicine, HELSAM, Institute of Health and Society, University of Oslo, P.o. Box 1130 Blindern, 0318, Oslo, Norway.
University of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFrail residents in the nursing home sector call for extra care in prescribing. The Norwegian General Practice Nursing Home (NORGEP-NH) list of 34 explicit criteria for potentially inappropriate medication use in nursing homes was developed explicitly for this population. The aim of this study was to employ the NORGEP-NH Criteria to study the extent of potentially inappropriate medication use among nursing home residents and explore possible associated factors.

methodsCross-sectional observational pharmacoepidemiological study from residents in nursing homes in the county of Vestfold, Norway. Data collected 2009-11 included residents' demographic and clinical status and all medications, regular and on demand.

results881 patients from 30 institutions (mean 85.9 years, 68.6% female), were included. According to NORGEP-NH, 43.8% were prescribed at least one potentially inappropriate regular medication, and 9.9% regularly received three or more potentially inappropriate medications. When also including a) the NORGEP-NH Deprescribing Criteria and b) including drugs prescribed for use as needed, 92.7% of all residents received medication that needs particular surveillance according to the NORGEP-NH. 69.7% of the nursing home residents used at least one psychotropic drug regularly. Female residents received more often than males at least one potentially inappropriate regular medication (OR 1.60, p=0.007). Regarding the prescription of three or more concomitant psychotropic medications, odds ratio for females was 1.79 (p=0.03) compared to males. Residents with the best performance in activities of daily living, and residents residing in long-term wards, had higher risk of using three or more psychotropic drugs. Use of multiple psychoactive drugs increased the risk of falls in the course of an acute episode of infection or dehydration (odds ratio 1.70, p=0.009).

conclusionsPrevalence of potentially inappropriate medications in nursing homes according to the NORGEP-NH was extensive, and especially the use of multiple psychotropic drugs. The high prevalence found in this study shows that there is a need for higher awareness of medication use and side effects in the elderly population.

trial registrationRetrospectively registered. Data obtained from clinical trial NCT01023763 registered with ClinicalTrials.gov 12/01/2009.

Indexed as

Homes for the AgedInappropriate PrescribingMedication ErrorsNursing HomesPotentially Inappropriate Medication ListAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleNorwayPharmacoepidemiologyPrevalencePsychotropic DrugsRetrospective StudiesPsychotropic DrugsDrug safetyElderlyExplicit criteriaNORGEP-NHNursing homesPotentially inappropriate medication usePsychotropic medications

Identifiers

PMID28927372
PMCPMC5606129
OpenAlexW2755878812

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.