Evidence map›Paper›PMID 28927259›Full record

ArticleMolecules and cells2017

Generation, Diversity Determination, and Application to Antibody Selection of a Human Naïve Fab Library.

Sangkyu Kim, Insoo Park, Seung Gu Park, Seulki Cho, Jin Hong Kim, Nagesh S Ipper, Sun Shim Choi, Eung Suk Lee, Hyo Jeong Hong

Abstract read
In one paragraph

Article in Molecules and cells, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
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  4. Structure and sequence engineering approaches to improve in vivo expression of nucleic acid-delivered antibodies.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
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  6. Article
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  9. Article
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  14. Review
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sangkyu KimDepartment of Systems Immunology, College of Biomedical Science, Kangwon National University, Chuncheon 24341, Korea.
Insoo ParkTherapeutic Antibody Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
Seung Gu ParkDepartment of Medical Biotechnology, College of Biomedical Science, Kangwon National University, Chuncheon 24341, Korea.
Seulki ChoTherapeutic Antibody Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
Jin Hong KimTherapeutic Antibody Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
Nagesh S IpperInstitute of Bioscience and Biotechnology, Kangwon National University, Chuncheon 24341, Korea.
Sun Shim ChoiDepartment of Medical Biotechnology, College of Biomedical Science, Kangwon National University, Chuncheon 24341, Korea.
Eung Suk LeeScripps Korea Antibody Institute, Chuncheon 24341, Korea.
Hyo Jeong HongDepartment of Systems Immunology, College of Biomedical Science, Kangwon National University, Chuncheon 24341, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We constructed a large naïve human Fab library (3 × 10

Indexed as

Amino AcidsAntibodiesAntibodies, MonoclonalAntigensHumansImmunoglobulin Fab FragmentsImmunoglobulin Heavy ChainsImmunoglobulin Light ChainsLymphocytesPeptide FragmentsPeptide LibraryAmino AcidsAntibodiesAntibodies, MonoclonalAntigensedratideImmunoglobulin Fab FragmentsImmunoglobulin Heavy ChainsImmunoglobulin Light ChainsPeptide FragmentsPeptide Librarydiversityhuman monoclonal antibodynaïve antibody libraryphage displaysomatic hypermutation

Identifiers

PMID28927259
PMCPMC5638773

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.